ESCRS - PO378 - Comparative Assessment Of The Morphometric Parameters With Using Optical Coherent Tomography In Patients With Open-Angle Glaucoma In Central Asia.

Comparative Assessment Of The Morphometric Parameters With Using Optical Coherent Tomography In Patients With Open-Angle Glaucoma In Central Asia.

Published 2022 - 40th Congress of the ESCRS

Reference: PO378 | Type: ESCRS 2022 - Posters | DOI: 10.82333/hh7z-rx37

Authors: Hulkar Abulkasimova* 1 , Iskandar Rasulov 1 , Gulnoza Goyibova 2

1Department of Ophthalmology,Tashkent Medical Academy,Tashkent,Uzbekistan, 2Department of Ophthalmology,Tashkent Pediatric Medical Institute,Tashkent,Uzbekistan

Purpose

To provide a comparative assessment of the morphometric parameters status of the optic nerve using optical coherence tomography in 80 patients (160 eyes) of POAG I, II and III stages with unstabilized increase and high IOP levels.

Setting

Compared estimation of the morphometric limitations with utilizing optical coherent tomography (OCT) in people who suffer from primary open-angle glaucoma (POAG) in Central Asia.

Methods

While 40 patients (80 eyes) of the control group received the Dorsamed during the treatment 3 times a day, another group of patients (40 patients, 80 eyes) have taken Azopt 2 times a day during 6 months of observation. 

Results

Data analysis for evaluating global volume loss revealed some decrease in the thickness of retinal ganglion cells in patients with the initial stages of POAG in 10.0% of patients in the control group and 6.7% of patients in the main group, which led to the conclusion of certain cellular “losses” in this layer of the retina, mainly in the upper-nasal and upper-temporal regions. Objective registration of the volume and area of ​​the neuroretinal belt did not disclose that how much a reliable decrease in the belt parameters for 6 months with continued treatment.

Conclusions

 In the process of treatment, there were no reliable morphometric changes in the foveolar zone and nerve fiber layer, indicators of the volume and area of ​​the neuro-retinal belt as well as the shape and depth of optic nerve excavation, which indicates stabilization of the glaucomatous process, normalization of intraocular pressure and adequate anti-glaucoma therapy. In general, it can be concluded that OCT is an effective method for diagnosing structural changes in the retina and the most sensitive method for diagnosing glaucoma.