Comparison Of Visual Outcomes Among Six Presbyopia-Correcting Intraocular Lenses After Cataract Surgery

To compare the defocus curve, contrast sensitivity, patient and doctor satisfaction among six different presbyopia-correcting intraocular lenses in Taiwanese population.

A prospective cohort study

In this prospective cohort study, patient who received phacoemulsification were divided into six groups according to the type of presbyopia-correcting intraocular lens [extended depth of focus (ZXR00), diffractive panfocal (PanOptix), diffractive bifocal (ZMB00 and ReSTOR), segmental refractive (Oculentis MF15 and Oculentis MF30)]. The uncorrected and best corrected visual acuity (VA), defocus curves, contrast sensitivity, patient and doctor satisfaction were measured at 1 months and 4 months postoperatively.

Total 263 patient was included. The uncorrected and corrected distant VA were not significantly different among the six groups. Regarding the defocus curve, ZXR00 had better VA from 2 meter (m) to 67 centimeters (cm) (P < 0.01) but yielded worse VA from 40 cm to 33 cm in the defocus curve (P < 0.001). While PanOptix provided better visual acuity from 50 cm to 33cm (P < 0.001). The contrast sensitivity in both mesopic and photopic condition were comparable among six groups. There was a significant higher patient satisfaction in the intermediate vision of ZXR00 group (P = 0.021), but no difference in other parameters. For spectacle independence, ZXR00 groups required more assistance of near glass. 

The extended depth of focus intraocular lens (ZXR00) offers a better intermediate visual acuity and contrast sensitivity than other presbyopia-correcting designs in this prospective study. While the panfocal PanOptix intraocular lens provides better visual acuity at near distance.