Evolux, The New Standard Of Care With Extended Depth Of Focus In Monofocal Intraocular Lenses.

The aim of the study is to evaluate the new extended monofocal intraocular lens, Evolux, conceived to allow patients greater comfort in their day-to-day activities through an enhanced depth of focus up to 1.5D. Evolux is thought to improve vision for intermediate tasks while maintains good distance vision and minimum photic phenomena compared to a standard aspheric monofocal IOL.

Business and Portfolio Development Department SIFI S.P.A, Catania, Italy.

The optic of Evolux lays its basis on a specific optimization of the patented spherical aberration technology already in use in Mini Well and Mini Well Proxa IOLs for an effective and manageable optical performance. This new optimized optic technology consists of no diffractive rings, 5 different refractive zones with spherical aberrations (SA) distribution of opposite signs in the 4.50 mm central zone, designed to improve intermediate vision and preserve distance vision regardless pupil size dimension. IOLs optical performance was tested at the optical bench and specific analyzer of image quality to investigate depth of focus, visual acuity, straylight analysis and sensitivity to tilt, decen­tration and angle Kappa.

The modulation transfer function through focus curves reveal an improvement in the depth of focus compared to a standard monofocal IOL maintaining a good distance vision. MTF for a 3mm pupil was 0.43 and 0.25 for far and intermediate vision respectively. No negative impact caused by decentration (±0.5mm), by tilt (±5 degrees) or pupil dimensions on MTF values is noticed for far and intermediate distances. Light distribution analysis using the Point Spread Function reveals that 99% of light falls within a spot of 20μm, with no scattered light causing reduced image contrast. A retinal charts simulator demonstrates that Evolux is tolerant to slight myopic and hyperopic shifts. Evolux optical microscopy observations show minimal glistening.

Evolux, the new extended monofocal intraocular lens, was evaluated through numerical simulations and experimental characterization. The applied optical technology provided an improved intermediate vision maintaining a well-performing distance vision, very low pupil dependency at far and intermediate distances, similar image contrast with different pupil dimensions. Moreover, Evolux  guarantees the safety of a standard monofocal IOL in terms of tilt and decentration and photic phenomena and, in addition, provides a good tolerance to residual refractive errors. In this way, the new extended monofocal IOL Evolux can help patients with their everyday activities, making everyday life easier.