Visual Performance And Proms Of A Novel Presbyopia-Correcting Iol With Wavefront-Shaping Technology Implanted In Patients With Glaucoma In A Real-World Registry Study

To report the real-world visual outcomes in subjects bilaterally implanted with AcrySof IQ Vivity or/and AcrySof IQ Vivity Toric presbyopia-correcting IOLs (models DFT015 and DFTX15-Toric). Here, we report outcomes for the subgroup with glaucoma.

Multicenter, ambispective registry study conducted in Europe, the UK, Australia and New Zealand evaluating the performance of bilaterally implanted AcrySof IQ Vivity and AcrySof IQ Vivity Toric IOL in a real world setting through routine clinical practice.

This is the second interim analysis of subjects participating in the study. After a minimum of 3 months of follow-up, visual performance of subjects comprising binocular uncorrected and best distance corrected visual acuities at distance, intermediate at 66 cm and near at 40 cm were measured. Patient-reported levels of spectacle independence, satisfaction and visual disturbances were collected.

To date, 18 subjects out of 757 subjects of the full cohort presented glaucoma and have been implanted bilaterally with DFT015 or DFTX15-Toric IOLs. At the study entry visit, binocular mean logMAR (SD) UCDVA was 0.015 (0.125), UCIVA 0.099 (0.141) and UCNVA 0.271 (0.115). Similarly, binocular mean BCDVA was -0.039 (0.113), DCIVA 0.068 (0.126) and DCNVA 0.290 (0.104). The majority of subjects (94.4%) never needed to wear spectacles for distance and

intermediate in bright conditions and ≥83.3% in dim conditions. High levels of satisfaction were observed, with 83.3% of subjects reporting that they were very satisfied with their sight. In addition, no halos, glare or starbursts were reported by 94.4%, 94.4% and 100% of subjects, respectively.

The initial results of this real-world assessment of subjects with glaucoma and bilaterally implanted with DFT015 and DFTX15-Toric IOL showed good distance, intermediate and near uncorrected and best distance corrected vision, very high levels of patient satisfaction, good levels of spectacle independence and very low levels of visual disturbances.