ESCRS - PO094 - Efficacy Of Hyaluronic Acid 0.15% Eye Drops To Improve Tear Film Stability And Ocular Discomfort In Patients Scheduled For Cataract Surgery

Efficacy Of Hyaluronic Acid 0.15% Eye Drops To Improve Tear Film Stability And Ocular Discomfort In Patients Scheduled For Cataract Surgery

Published 2022 - 40th Congress of the ESCRS

Reference: PO094 | Type: ESCRS 2022 - Posters | DOI: 10.82333/gfze-ak59

Authors: Francesco Blasetti* 1 , Franco Spedale 1

1Asst-Franciacorta,Chiari,Italy

Purpose

The aim of the study was to retrospectively evaluate the efficacy of hyaluronic acid 0.15% eye drops in terms of improving tear film stability and ocular discomfort when administred 8 weeks before cataract surgery until 8 weeks after, compared with the same drops administered for 8 weeks after surgery

Setting

Forty-four eyes of 44 patients underwent uncomplicated cataract surgery performed by the same surgeon at the Ophthalmology Operating Unit of Chiari Hospital (BS), Italy, from September to October 2021

Methods

Forty-four eyes of 44 patients were divided into two groups: group A included 22 patients who received topical hyaluronic acid 0.15% eye drops 3 times per day in both eyes from 8 weeks before cataract surgery until 8 weeks after; group B included 22 patients who started the same drops from the day of cataract surgery until 8 weeks after. All patients followed the same postoperative steroid and antibiotic and anti-inflammatory topical regimen. Tear Break-Up Time (BUT), Corneal Fluorescein Staining (CFS), and Ocular Surface Disease Index (OSDI) were assessed 8 weeks before surgery, 2 days, and finally 8 weeks after. All patients had zero to mild ocular symptoms detected using the OSDI. The two groups were well matched

Results

No statically significant differences were detected between the two groups 8 weeks before surgery and 2 days after. Eight weeks after surgery, patients in group A showed a greater increase in BUT and a lower OSDI score compared with those in group B (p<0.05). No significant differences were found between the two groups regarding CFS

Conclusions

Hyaluronic acid 0.15 % eye drops were effective in reducing symptoms of dry eye disease after cataract surgery. Better results appear to be obtained when patients are treated starting at least 8 weeks before cataract surgery. Larger studies are needed to confirm this preliminary finding