ESCRS - PO034 - Use Of A Topical Insulin For Neurotrophic Corneal Ulcer After The Pars Plana Vitrectomy - Case Report

Use Of A Topical Insulin For Neurotrophic Corneal Ulcer After The Pars Plana Vitrectomy - Case Report

Published 2022 - 40th Congress of the ESCRS

Reference: PO034 | Type: Case report | DOI: 10.82333/aq3n-fz15

Authors: Marcin Jaworski* 1 , Rafał Leszczyński 2 , Ewa Mrukwa-Kominek 3

1Department of Opthalmology,Professor K. Gibiński University Hospital Centre, Medical University of Silesia, Poland ,Katowice,Poland, 2Department of Opthalmology,Professor K. Gibiński University Hospital Centre, Medical University of Silesia, Poland,Katowice,Poland, 3Department of Opthalmology,Professor K. Gibiński University Hospital Centre, Medical University of Silesia, Poland,Katowice,Poland;Department of Opthalmology,School of Medicine in Katowice, Medical University of Silesia,Katowice,Poland

Evaluation of treatment with topical insulin of a refractory neurotrophic corneal ulcer after multiple vitrectomies

Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Poland; 01-02/2022

The study analyzed the effectiveness of the compound drops of insulin for corneal ulcers of 62-year old male. We assessed the ulcer using a corneal topographer, an anterior OCT. Additionally, we used a photographic program to analyze images of the anterior segment after fluorescein staining of the cornea to assess changes in the ulcer surface area. Due to pharmacologically-resistance glaucoma after ulcer healing, a transscleral cyclodestruction (TSCPC) was performed. We achieved complete resolve of the corneal ulcer after 3 days of topical insulin therapy. In a month-long follow-up, the intraocular pressure was normalized and stable after the TSCPC. The cornea healed with a discrete central scar.

Our study shows that topical insulin can be an effective treatment for persistent corneal ulcers. Glaucoma may interfere with the assessment of results. It is recommended to test a larger number of cases.