Comparison Of Intraocular Pressure Lowering Effect And Complications Between Istent Inject W And Istent

The early postoperative results of the iStent inject w^® (GLAUCS, IW) and iStent^® (GLAUCS, IS) were reported at the 45th Japanese Society for Ophthalmic Surgery Congress. To include longer-term results and complications by extending the observation period.

Patients with open-angle glaucoma and cataract were included in the Saitama Red Cross from July 2017 to July 2021.

We included 179 eyes (male: 86, female: 93, mean age: 73.2±7.2 years) that underwent intraocular drainage surgery with lens reconstruction (Drainage) using IW and IS. They were follow-up available at least 12 months after surgery. Pre- and postoperative intraocular pressure (IOP), the number of glacoma medication (Med), and complications were compared.

IOP and Med at baseline were 16.1±3.5 mmHg and 2.4±1.1 in IW and 17.9±3.3 mmHg and 2.2±1.1 in IS. IOP and Med at 12 months postoperatively were 13.8±2.5 mmHg and 0.9±0.9 in IW and 14.7±2.1 mmHg and 1.5±1.1 in IS. There were no significant differences in the rate of IOP reduction in two groups within 12 months. (p=0.11 ~ 0.36) Med was significantly lower in IW than IS within 12 months postoperatively. (p<0.05 ~ <0.001) In complications, hyphema with clots and transient IOP elevation were 5.1% and 1.7% in IW and 1.1% and 1.1% in IS with no significant differences. (p=0.2 and 1.0, respectively)

In intraocular drainage surgery combined with lens reconstruction, IW was thought to provide better IOP reduction than IS in the form of a significant reduction in MED while maintaining safety.