ESCRS - FPS10.08 - Safety Of Epithelium-Off Corneal Cross-Linking For Keratoconus Performed In An Office-Based Setting

Safety Of Epithelium-Off Corneal Cross-Linking For Keratoconus Performed In An Office-Based Setting

Published 2022 - 40th Congress of the ESCRS

Reference: FPS10.08 | Type: Free paper | DOI: 10.82333/n91c-q135

Authors: Farhad Hafezi* 1 , Emilio A. Torres-Netto 1 , Léonard Kollros 2 , Nikki L. Hafezi 1 , Mark Hillen 1

1ELZA Institute AG,Dietikon,Switzerland, 2ELZA INSTITUTE AG,Dietikon,Switzerland

Purpose

To assess the safety of epithelium-off corneal cross-linking (epi-off CXL) in an office-based setting.

Setting

ELZA Institute, Zurich, Switzerland

Methods

We compared the complication rates of epithelium-off corneal cross-linking (epi-off CXL) performed in an office-based setting to those of epi-off CXL performed in an operating room. Consecutive epi-off CXL procedures (n=511), performed by a single surgeon in a procedure room at the ELZA Institute, Zurich, Switzerland.

Results

No cases of postoperative infectious keratitis were observed, and sterile infiltrates occurred in 10/511 (1.95%) of patients, all of whom responded well to topical steroid therapy. Delayed epithelialization (>7 days) occurred in 14/511 (2.74%) patients. No other adverse events were noted.

Conclusions

Office-based epi-off CXL does not seem to be associated with an increased complication risk when compared to operating room settings.