Contralateral Implantation With A Small-Aperture Iol: Assessing Long-Term Visual Outcomes And Stability

To evaluate the stability of visual acuity performance in cataract patients after a one-year period following contralateral implantation with a small-aperture intraocular lens (IOL) and a monofocal or monofocal toric IOL compared to bilateral implantation of monofocal or monofocal toric IOLs.

Prospective, multi-center, parallel group, non-randomized, clinical trial.

Cataract patients in the IC-8 group (N=343) received an IC-8 small aperture IOL in combination with a monofocal or monofocal toric IOL in their fellow eye. The IC-8 IOL eye had a myopic refractive target of -0.75 D while the fellow eye was targeted for plano. The Control Group (N=110) patients were bilaterally treated with monofocal or monofocal toric IOLs targeting plano. Mean monocular and binocular uncorrected distance (UCDVA), intermediate (UCIVA), and near (UCNVA) as well as manifest spherical refractive equivalent (MRSE) were reported at 12 months post-op. Results are presented in mean logMAR + standard deviation with Snellen equivalent.

At 12 months, UCDVA in the IC-8 IOL eye was 0.12 + 0.14 (20/26), UCIVA was 0.10 + 0.19 (20/25) and UCNVA was 0.22 + 0.15 (20/33). Mean UCDVA, UCIVA and UCNVA in the fellow monofocal eye was 0.03 + 0.12 (20/21), 0.30 + 0.18 (20/40) and 0.50 + 0.17 (20/63). Binocularly IC-8 patients achieved -0.02 + 0.10 (20/19) for UCDVA, 0.07 + 0.16 (20/23) for UCIVA, and 0.19 + 0.14 (20/31) for UCNVA. Monocular and binocular UCIVA and UCNVA for the IC-8 group was statistically superior over the Control Group (p < 0.05) at the 12-month visit. Mean MRSE reported for IC-8 eye was -0.32 D + 0.48 and 0.12 D + 0.37 in the fellow eye.

Patients contralaterally treated with a small-aperture IOL and monofocal or monofocal toric IOL achieved equivalent distance vision and statistically significantly superior intermediate and near vision at the long-term follow-up compared to patients treated with monofocal IOLs.