Large Cohort Analysis From A Multi-Country Registry Assessment Of Real World Visual Performance And Patient Satisfaction Outcomes Of A Novel Wavefront Shaping Presbyopia-Correcting Iol

To report real world visual outcomes and patient satisfaction in a large cohort implanted bilaterally with Acrysof IQ Vivity and/or Acrysof IQ Vivity Toric presbyopia correcting IOL models DFT015, DFT215, DFT315, DFT415, and DFT515.

Multicenter, ambispective registry study conducted in Europe, the UK, Australia and New Zealand evaluating the performance of bilaterally implanted AcrySof IQ Vivity and AcrySof IQ Vivity Toric IOL in a real world setting through routine clinical practice. This cohort includes 4% post corneal refractive surgery subjects and 25% with ocular comorbidities. 

After a minimum of 3 months post-op follow up after second eye surgery per local clinical practice standards, subjects implanted with the AcrySof IQ Vivity and/or Vivity Toric IOL in both eyes underwent visual performance assessments of visual acuity at distance, intermediate (66 cm) and near (40 cm). Subject satisfaction and spectacle independence recorded via validated questionnaires and patient reports of visual disturbances are reported. 

To date, 757 subjects aged 66.9 (9.52) years were enrolled. Binocular mean UCDVA was 0.014 ± 0.102 logMAR (20/20 Snellen), mean UCIVA was 0.085 ± 0.122 logMAR (~ 20/25 Snellen) and mean UCNVA was 0.247 ± 0.158 logMAR (~20/32 Snellen). 91.4% of patients reported to be satisfied with their sight and 75.3% report no difficulty seeing the prices of goods when shopping. The % of subjects reporting never/rarely needing to wear eyeglasses to see up close was 59.4%, or at arm’s length 88.7% or far away 92.9%.  Subjects reporting “None” for halos was 91.8%, glare 92.1% or starbursts 94.9%. Up to 12 months follow-up 3.2% of subjects required posterior capsulotomy. No ocular serious adverse events were reported.

In this large cohort real world study of patients bilaterally implanted with AcrySof IQ Vivity and/or AcrySof IQ Vivity Toric presbyopia correcting IOLs, we have observed very good distance (20/20), intermediate (~20/25), and functional near visual acuity (~ 20/32) outcomes. Very high percentages of spectacle independence from distance to intermediate, great subjects’ visual satisfaction with patients reporting none or low difficulty to perform daily activities as well as very low visual disturbances.