ESCRS - FPM11.01 - Increasing Depth Of Focus With Allogenic Presbyopic Inlays: Three-Year Results

Increasing Depth Of Focus With Allogenic Presbyopic Inlays: Three-Year Results

Published 2022 - 40th Congress of the ESCRS

Reference: FPM11.01 | Type: Free paper | DOI: 10.82333/f4jf-q136

Authors: Fatma Feyza Nur Keskin Perk* 1 , Suphi Taneri 2 , Cafer Tanrıverdi 1 , Sezer Hacıağaoğlu 1 , Zeki Yiğit Karaca 1 , Aylin Kılıç 1

1Ophtalmology,Medipol Mega University Hospital,İstanbul,Türkiye, 2Augenzentrum am St. Franziskus Hospital Münster,Münster,Germany

Purpose

To compare defocus curves of treated and fellow eyes and demonstrate the increase in depth of focus provided by an allogenic corneal inlay designed to modify the anterior surface shape of the central cornea

Setting

Istanbul Medipol University School of Medicine, Ophthalmology Department, Istanbul, Turkey

Methods

This retrospective case series includes 52 eyes of 26 patients with a follow-up of 3 years. Emmetropic patients with presbyopia who required a reading addition from +1.50 to +2.50 diopters(D) and had less than 20/40 uncorrected near vision had implantation of allogenic corneal inlays (Allotex) of 3 mm diameter and 40 µm central height in the nondominant eye. Uncorrected and best corrected distance visual acuity (UCDVA,BCDVA), and uncorrected near visual acuity (UCNVA) were evaluated in all eyes. Multifocal Lens Analyzer 3.0 application (Q Vision Academy) was used to analyze the depth of focus and create defocus curves. The areas under the curve for the far (AUCF), intermediate (AUCI), and near (AUCN) distance between two eyes were compared.

Results

At 3 years, UCDVA, BCDVA, UCNVA values were 0.88±0.16, 0.97±0.04, 0.82±0.22 (Snellen), respectively, in treated eyes, while they were 0.93± 0.12, 0.99± 0.02, 0.31± 0.14, respectively, in fellow eyes. There was no significant difference between treated and fellow eyes in UCDVA and BCDVA, whereas UCNVA was statistically better in the treated eyes (p=0.29, p=0.10, p<0.01, respectively). In addition, the area under the curve was better in near, intermediate and total in treated eyes, while it was better in far in fellow eyes. All values were statistically significant (p= 0.023 total, p<0.01 others). The depth of focus range of the treated eyes was 4D, while in the fellow eyes it was 2.5D.

Conclusions

At 3 years, allogenic presbyopic lenticule implantation provided a clinicaally and statistically significant increase in depth of focus by expanding the width of the plateau in the defocus curve. The compromise in distance visual acuity was acceptable.