Smile-800 For Low To Moderate Myopia In Comparison With Smile-500.

To compare the effectiveness, safety and stability of the results of SMILE procedure with the Visumax-800 femtosecond laser with the same Smile procedure on the Visumax-500 femtosecond laser, for low to moderate myopia

: Dr. Solomatin Eye Center , Latvian University, Riga, Latvija.

In this prospective non-randomized case-control study, patients with low to moderate myopia were assigned to the SMILE-800 group (cases) or the SMILE-500 group (controls). In the SMILE-800 group, 60 eyes were treated using the new Visumax-800 femtosecond laser ( Zeiss-Meditec GmbH , Germany). Outcome measures included, uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), manifest refraction, and safety and efficacy indexes which were compared between the study groups.

One hundred twenty eyes of 60 patients were enrolled in this study. Each study group comprised of 60 eyes of 30 patients. Mean UCVA was significantly better in the SMILE-800 case group than in the control group at the postoperative month 2 (P = 0.01). Regarding the safety and efficacy indexes, the SMILE-800 group had better results than the SMILE-500 group (P < 0.01 for both comparisons). The docking time was shorter in the SMILE-800 group (11 sec.), neither in the SMILE-500 group (28 sec).

The SMILE procedure with Visumax-800 femtosecond laser, seems to be superior to the SMILE procedure with Visumax-500 femtosecond  laser, for the treatment of low to moderate myopia in terms of docking time, visual recovery and safety and efficacy indexes.