ESCRS - FPM04.02 - Frequency And Risk Factors Of Narrow Angles In Patients With Pseudoexfoliation: A Case-Control Study

Frequency And Risk Factors Of Narrow Angles In Patients With Pseudoexfoliation: A Case-Control Study

Published 2022 - 40th Congress of the ESCRS

Reference: FPM04.02 | Type: Free paper | DOI: 10.82333/sfk3-v448

Authors: Ibrahim Abdulkarim Alobaida* 1

1Glaucoma,King Khaled Eye Specialist Hospital,Riyadh,Saudi Arabia

Purpose

To determine the frequency and risk factors of narrow angles in pseudoexfoliation (PXF) patients.

Setting

A prospective case-control study was conducted during the period from March 2017 to December 2020. 

Methods

Adult patients (above 40 years) presenting with PXF were consecutively enrolled (study group). Cases were matched with individuals above 40 years presenting to a comprehensive ophthalmology clinic without evidence of PXF (control group).

Results

We enrolled 196 PXF patients and 98 controls. The occurrence of narrow angles was 25% in the PXF group and 5.1% in the control group (P = 0.0001). Compared to controls, PXF patients were older (72.6 ± 9.6 vs. 64.4 ± 8.5, P < 0.0001) and had a lower mean ACD (2.79 ± 0.4 vs. 3.05 ± 0.4, P < 0.0001). There was no difference in AL measurements between both groups (23.3 ± 1.4 vs. 23.7 ± 1.0, P = 0.0714). After stratification by age group and gender, the risk of narrow angles was higher in PXF patients above 70 years (OR, 4.15; 95% CI, 0.91-23.87; P, 0.044). There was no gender difference in the risk of developing narrow angles.

Conclusions

Narrow angles are more frequently encountered in PXF patients compared to controls. Advanced age (> 70 years) is significantly associated with an increased likelihood of developing narrow angles.