ESCRS - P255 - OCT PARAMETERS OF CENTRAL RETINA IN CORONARY ARTERY DISEASE PATIENTS AND CONTROLS

OCT PARAMETERS OF CENTRAL RETINA IN CORONARY ARTERY DISEASE PATIENTS AND CONTROLS

Published 2022 - 26th ESCRS Winter Meeting

Reference: P255 | Type: Abstracts | DOI: 10.82333/f4mz-z376

Authors: Indrė Matulevičiūtė* 1 , Agnė Sidaraitė 1 , Dalia Žaliūnienė 1

1Department of Ophthalmology,Hospital of the Lithuanian University of Health Sciences Kaunas Clinics,Kaunas,Lithuania

Purpose

To evaluate the parameters of foveal optical coherence tomography (OCT) in patients with coronary angiography performed.

Setting

The study was performed in the university hospital between February of 2019 and October of 2021.

Methods

174 participants after initial cardiologic evaluation and coronary angiography were included in the study. According to the indications and the results of coronary angiography, all  participants were separated into 3 groups – acute coronary syndrome (ACS, N=76), no changes in coronary angiography (control, N=76) and three vessel disease without previous major coronary events (3VD). All the patients were ophthalmologically examined afterwards. OCT scans of the macula were performed using swept source OCT in addition to standard ophthalmic examination. Retinal and choroidal thickness in ETDRS segments (central, both inner and outer nasal, temporal, superior and inferior ) were calculated automatically by the software. The regional ethical committee of Kaunas approved the research protocol. The tenets of the Declaration of Helsinki were confirmed by the research. The results are expressed as mean and standard deviation. Written informed consent was obtained from participants.

Results

Retinal thickness was statistically significantly greater in control group in comparison to 3VD group in the outer circle of ETDRS segments (286.13;18.189 vs. 275.27;13.228; 262.12;14.932 vs. 253.23;12.386; 273.09;15.492 vs. 264.73;12.646; 263.97;16.112 vs. 253.68;12.785, p <0.05) and in comparison to ACS group in inner temporal (303.26;16.554 vs. 297.29;15.636), superior (313.99;16.580 vs. 309.16;14.569) inferior (311.04;16.815 vs. 305.76;16.864) and outer temporal (262.12;14.932 vs. 255.41;13.547) segments (p<0.05). Comparison of the choroidal thickness values between the groups showed that the choroid of 3VD group was statistically significantly thinner  in all ETDRS segments except outer superior segment in comparison to ACS group (p<0.05) and thinner  in all ETDRS segments except inner superior segment where 3VD group had thicker choroid in comparison to control group (p<0.05).

Conclusion

The findings of our study suggest that central choroidal and retinal thickness may be important markers of coronary artery disease (the thinning of the retina and choroid is greater with the higher number of coronary arteries affected). The results could be used as a screening tool for coronary artery disease after further research.