ORBITAL METASTASIS OF AN UNDIFFERENTIATED NASOPHARYNGEAL CARCINOMA: A CASE REPORT

Published 2022 - 26th ESCRS Winter Meeting

Reference: P253 | Type: Abstracts | DOI: 10.82333/e2sz-j954

Authors: Saida Laababsi* ¹ , Soukaina Bouziane ² , Sara El Hachimi ¹ , Adil Mchachi ¹ , Laila Benhmidoune ¹ , Abderrahim Chakib ¹ , Rayad Rachid ¹ , Mohamed El Belhadji ¹

¹Ophthalmology,Hospital August 20,Casablanca,Morocco, ²Ophthalmology,Hospital august 20,Casablanca,Morocco

Purpose

The aim of this work is to present a case rarely reported in the literature of nasopharyngeal carcinoma (NPC) revealed by an orbital invasion, and is found in a relatively low percentage of patients with orbital tumour.

Setting

Adult ophthalmology department, hospital August 20, Casablanca, Morocco.

Methods

Patient 58 years old, treated for nasopharyngeal carcinoma 2 years ago, declared in remission, who presents at the consultation for right exophthalmos which worsens with time, with a redness and visual blur evolving since 2 months. The clinical examination finds on the right eye a decrease of the visual acuity (4/10), total ophtalmoplegia and papillary edema at the fundus examination.

Results

A Computed tomography scan (CT scan) of the face was requested which revealed a well-limited oval-shaped right intra-conical tissue process enhanced by contrast injection, invading the optic nerve and oculomotor muscles, coming into contact with the posterior pole of the eyeball, measures 42/30/37.3 mm. A magnetic resonance imaging (MRI) was requested that confirmed the orbital extension of the tumor process. Histopathological examination of the mass found undifferentiated nasopharyngeal carcinoma UCNT (Undifferenciated Carcinoma of Nasopharyngeal Type). The extension assessment was requested and a concomitant chemo-radiotherapy protocol was instituted. The evolution was good with a regression of the intra-orbital tumor mass with a decline of 6 months.

Conclusion

NPC with orbital extension remains a rare entity, but this diagnosis must be considered especially in the presence of ophthalmological signs. Therapeutic protocols must be adapted to each case and take into account the extent of the disease.