TEAR FILM, OCULAR SURFACE AND CORNEAL EPITHELIAL ALTERATIONS MEASURED BY ANTERIOR SEGMENT OPTICAL COHERENCE TOMOGRAPHY IN CHRONIC SMOKERS
Published 2022
- 26th ESCRS Winter Meeting
Reference: P132
| Type: Abstracts
| DOI:
10.82333/kw3g-1n29
Authors:
Ana Rita Carreira* 1
, Sandra Rodrigues-Barros 1
, Júlia Cunha Silva 2
, Matilde Ferreira de Almeida 2
, Pedro Carreira 1
, Filipe Moraes 1
, Inês Machado 1
, Paul Campos 1
, João Cardoso 1
, Nuno Campos 1
1Ophthalmology,Hospital Garcia de Orta, E.P.E,Almada,Portugal, 2Pneumology,Hospital Garcia de Orta, E.P.E,Almada,Portugal
Purpose
Our aim was to assess the effect of smoking habits on ocular surface, tear film stability and corneal epithelial thickness (CET).
Setting
Hospital Garcia de Orta E.P.E, Almada, Portugal
Methods
This study included healthy age-matched non-smokers and current cigarette smokers. Signs (Schirmer test I, Tear Film Break-up Time Test (TBUT), corneal fluorescein staining (CFS) score) and symptoms (Ocular Surface Disease Index (OSDI) questionnaire) of dry eye disease (DED) were evaluated, in accordance with the International Dry Eye WorkshopII criteria of DED. CET map was also assessed (Cirrus HD-5000Ò).
Results
Twenty eyes were included in the Non-smokers group, with a mean age of 40.03±6.78 years, and 21 in the Smokers group, with a mean age of 42.24±3.51 (p=0.08). Smokers group had higher OSDI (10.60±2.12 vs 14.27±2.60, p=0.04) and CFS score (3.01±0.42 vs 7.00±1.03, p=0.001) and lower TBUT values (12.23±1.34 vs 5.42±1.76s, p<0.001). Proportion of DED diagnosis (10 vs 100%, p<0.001) was higher in smokers. Superior CET measurements were lower in Smokers group (p<0.05). Smoking index was correlated with TBUT and superior and temporal CET measurements (p<0.05).
Conclusion
Smoking has a negative impact on ocular surface and corneal epithelial thickness, with a higher level of eye dryness and corneal thinning. These findings tend to be globally more severe in patients with greater cumulative exposure.