ESCRS - FP16 - EVALUATION OF CORNEAL ENDOTHELIUM AFTER MYOPIC LASER-ASSISTED IN SITU KERATOMILEUSIS (LASIK) WITH ACCELERATED CROSS-LINKING (CXL) IN DIABETIC PATIENTS.

EVALUATION OF CORNEAL ENDOTHELIUM AFTER MYOPIC LASER-ASSISTED IN SITU KERATOMILEUSIS (LASIK) WITH ACCELERATED CROSS-LINKING (CXL) IN DIABETIC PATIENTS.

Published 2022 - 26th ESCRS Winter Meeting

Reference: FP16 | Type: Abstracts | DOI: 10.82333/7gp0-2a42

Authors: Mohamed Mahmoud* 1 , Ahmed Abdelhalim 2 , Ebtesam Ammar 2

1Opthalmology,Minia,Minia,Egypt;Opthalmology,Minia,Minia,Egypt, 2Opthalmology,Minia,Minia,Egypt

Purpose

to study the effect of LASIK with accelerated CXL on corneal endothelium in myopic diabetic patients.

Setting

A prospective comparative interventional case series study on 120 eyes of 60 myopic patients treated with LASIK with accelerated CXL. They were divided into two groups, group A included 60 eyes of diabetic patients, group B included 60 eyes of non-diabetic patients. Corneal endothelium was evaluated by specular microscope preoperatively and after 3 and 6 months postoperatively

Methods

A prospective comparative interventional case series study on 120 eyes of 60 myopic patients treated with LASIK with accelerated CXL. They were divided into two groups, group A included 60 eyes of diabetic patients, group B included 60 eyes of non-diabetic patients. Corneal endothelium was evaluated by specular microscope preoperatively and after 3 and 6 months postoperatively

Results

The endothelial cells density (ECD) showed statistically significant changes after 3 and 6 months postoperatively (p-value <0.001) in group A while group B showed statistically significant changes after 3 months without significant change after 6 months (p-value= 0.103), both groups had improved to near preoperative levels, with no significant differences between them at the end of 6 months follow-up (p-value = 0.219). Regarding pleomorphism, there was a significant change in group A during 6 months follow-up (p-value <0.001) with no significant change in group B (p-value= 0.884), and in comparing both groups, there was a significant change at the end of 6 months follow-up (p-value <0.001). Regarding polymegathism, there was a significant change in group A during 6 months follow-up (p-value <0.001) with no significant change in group B after 3 (p-value= 0.178) and 6 (p-value= 0.866) months follow-up and in comparing both groups, there was a significant change at the end of 6 months follow-up (p-value <0.001).

Conclusion

LASIK with accelerated CXL is safe on corneal endothelium in diabetic myopic patients but needs to follow up for a long period.