ESCRS - FP03 - COMPLICATIONS OF CATARACT SURGERY: UVEITIS-GLAUCOMA-HYPHEMA SYNDROME

COMPLICATIONS OF CATARACT SURGERY: UVEITIS-GLAUCOMA-HYPHEMA SYNDROME

Published 2022 - 26th ESCRS Winter Meeting

Reference: FP03 | Type: Abstracts | DOI: 10.82333/amya-5773

Authors: Laura Armonaite* 1 , Anders Behndig 2

1St Erik Eye hospital,Division of Ophthalmology and Vision, Karolinska Institutet,Stockholm,Sweden, 2Umeå University Hospital,Department of Clinical Sciences/Ophthalmology,Umeå,Sweden

Purpose

To assess underlying risk factors, clinical picture and IOL-iris contact signs in Uveitis-Glaucoma-Hyphema syndrome (UGH).

Setting

St. Erik Eye Hospital, Stockholm, Sweden.

Methods

In a retrospective case-control study with a cross-sectional component, 3 groups with 71 patient each were compared: UGH syndrome, dislocated IOL without UGH and ordinary pseudophakia. Main outcome measures were IOL-iris contact signs (iris defects, pseudophacodonesis, IOL dislocation and malposition) and use of blood thinners.

Results

Blood thinners were not more frequent in the UGH group (P=0.1). Iris defects were not more frequent in the UGH than in the Dislocated group but their form differed significantly (P<0.0001). Pseudophacodonesis (22.5 %) occurred more frequently in UGH than in ordinary pseudophakia (P=0.001). IOL with one haptic or entire 1-piece IOL in ciliary sulcus was observed only in the UGH group (30 %). UGH manifested as intraocular hemorrhage in 91 % of patients, while 8 % had iritis, pigment dispersion or macular edema. UGH syndrome mimicked other diagnoses in 13% of cases. 

Conclusion

Pseudophacodonesis and 1-piece IOL implantation in the ciliary sulcus are risk factors for UGH, meanwhile blood thinners are not. Iris defects are not specific to UGH unless they are formed like the IOL haptic or optic edge. UGH syndrome has a large clinical variety.