INCIDENCE OF PSEUDOPHAKIC CYSTOID MACULAR OEDEMA OVER A DECADE IN THE CATARACT SERVICE AT MOORFIELDS EYE HOSPITAL
Published 2026 - 30th ESCRS Winter Meeting
Reference: PP02.06 | Type: Presented Poster & Poster | DOI: 10.82333/k5j9-5r54
Authors: Alasdair Warwick 1 , Hussein Ibrahim 2 , Mehmet Ozturk 2 , Laxmi Raja 2 , Alex Ionides* 2
1University College London,London,United Kingdom, 2Moorfields Eye Hospital,London,United Kingdom
Purpose
To describe the incidence of pseudophakic cystoid macular oedema (PCMO) following routine uncomplicated cataract surgery over the past decade at a tertiary eye specialist centre.
Setting
The Cataract Service at Moorfields Eye Hospital, London, UK.
Methods
A retrospective review of routine uncomplicated cataract surgery cases from September 2012 to May 2025 was performed. PCMO cases were ascertained programmatically from electronic medical records (OpenEyes). Positive cases were defined as a clinic letter documenting "CMO" or "cystoid macular oedema" within 4 months after surgery and a concurrent prescription for ketorolac. This definition was validated by manual review of 90 randomly selected cases, confirming a true positive rate of 95.6% (86/90). Cases were excluded if patients had diabetes, received non-standard intraocular lenses, or underwent additional concurrent procedures.
Results
A total of 141,875 eyes from 97,587 patients were included. A statistically significant increase in the incidence of PCMO was observed from 2012 to 2025 (Chi-squared test for trend, p < 0.001). The rate rose from 0.7% (19/2,543) in 2012 to 1.5% (140/9,450) in 2015 and remained relatively stable (1.4-1.9%) until 2020. This was followed by a sharper increase from 1.7% (86/5,143) in 2020 to a peak of 4.4% (350/8,041) in 2023. The incidence then appeared to plateau at 4.0% in 2024 (324/8,064) and 4.0% (104/2,574) in the partial data for 2025.
Conclusion
The documented incidence of PCMO in the Cataract Service increased from 2012, appearing to plateau in the last three years (2023-2025) at approximately 4.0-4.4%. Further investigation is required to determine whether this observed trend represents a true increase in disease incidence or is an artifact of increased detection, possibly from more frequent use of optical coherence tomography.