6 YEAR EXPERIENCE WITH THE ENDOTHELIAL KERATOPROSTHESIS IMPLANTATIONS IN THE NETHERLANDS

To report follow up data on the Dutch EndoArt cohort with up to 6 years results of implantation with the

EndoArt (Eye Yon Medical, Israel) in terms of visual acuity, safety, device adherence, corneal clearing and thinning, and adverse

effects.

Cornea services at the Ophthalmology department of 2 Academic Institutions.

Consecutive interventional case series. The EndoArt is a dome shaped acrylic implant of 6.5 mm diameter, intended for replacement of dysfunctional endothelium. The EndoArt acts as physical barrier and prevents fluid uptake into the cornea. The barrier allows for stromal deturgescence leading to a new equilibrium & decrease in corneal thickness. The EndoArt was implanted in 20 eyes of 19 patients for indications of corneal edema. In 9 out of 20 eyes the indication was tectonic, because of complex ocular pathology. Longitudinal follow up of implanted cohort. 

Follow-up ranged from 5-60 months. In 18/20 eyes the EndoArt remained adherent. In most eyes a temporary

corneal suture was used to aid initial adherence, which reduced rebubbling rates. No immediate perioperative or post

operative complications occurred; especially not pathological thinning of the cornea was seen. In 1 eye a retinal

detachment occurred at 44 months.  A mean increase of visual acuity of logMAR from 1.99 to 1.05 was seen, even though this was not expected in the most complex eyes. Mean Central corneal thickness decreased 19,3%. In 1 patient no effect was

seen. In 2 patients the EndoArt failed to adhere. In 16 of 20 patients a suture was used, which lead to better and

earlier adhesion of the EndoArt.