VISUAL AND PATIENT-REPORTED OUTCOMES AFTER NON-DIFFRACTIVE PRESBYOPIA-CORRECTING, WAVEFRONT-SHAPING INTRAOCULAR LENS IMPLANTATION: A RETROSPECTIVE COHORT STUDY
Published 2026 - 30th ESCRS Winter Meeting
Reference: FP02.06 | Type: Free Paper | DOI: 10.82333/pgdv-bc28
Authors: Filomena Palmieri* 1 , Gabriele Gallo Afflitto 2 , Lorenzo Fabozzi 3 , Raphael Andreas Kilian 1 , Vincenzo Maurino 1
1Moorfields Eye Hospital NHS Foundation Trust,London,United Kingdom, 2Moorfields Eye Hospital NHS Foundation Trust,London,United Kingdom;University of Rome “Tor Vergata",Rome,Italy, 3Guy's and St Thomas' NHS Foundation Trust,London,United Kingdom;Moorfields Eye Hospital NHS Foundation Trust,London,United Kingdom
Purpose
To evaluate visual, refractive, and patient-reported outcomes after implantation of a nondiffractive, wavefront-shaping extended-range intraocular lens (IOL) in routine clinical practice.
Setting
Moorfields Eye Hospital NHS Foundation Trust, Private Branch, London, UK.
Methods
Retrospective consecutive cohort of 333 patients (597 eyes) undergoing cataract surgery with Vivity IOL implantation by 8 surgeons at the same institution. The cohort included patients with and without ocular comorbidities and with or without prior laser vision correction. Primary endpoints were postoperative uncorrected and corrected distance visual acuity (UDVA, CDVA) and spherical equivalent (SE) at 15–90 days. Secondary outcomes included binocular visual acuity, refractive accuracy, astigmatic vector analysis, complications, and Vision Correction Questionnaire (VCQ) results from a single-surgeon subset. Surgical strategies included immediate sequential and delayed sequential bilateral cataract surgery (ISBCS and DSBCS).
Results
Postoperative UDVA was 0.09 ± 0.14 and CDVA 0.01 ± 0.09 logMAR (both P<0.001). UNVA improved from 0.58 ± 0.39 to 0.43 ± 0.19 logMAR (P<0.001); DCNVA was unchanged (P=0.794). Binocular UDVA averaged 0.02 ± 0.08 logMAR; binocular UNVA was 0.31±0.21 logMAR. SE shifted from −1.07 ± 3.86 D to −0.30 ± 0.43 D (P<0.001); 84% and 96% of eyes were within ±0.50 D and ±1.00 D of target. Cylinder decreased from −0.81 ± 0.78 D to −0.40 ± 0.32 D (P<0.001), with vector analysis indicating effective astigmatism control. Intraoperative complications occurred in 0.8% of eyes (3 zonular dialysis, 1 Descemet membrane detachment, 1 IOL replaced). Postoperative complications (6.2%) included dysphotopsia (1.17%), posterior capsular opacification (1.01%), ocular hypertension (1.01%), and cystoid macular edema (0.5%); no toric repositioning was required. Outcomes were consistent across prior laser correction, axial length, and surgical strategy. VCQ data (n=65) showed high satisfaction (94%), minimal severe symptoms (<2%) limited to isolated cases of reduced visual comfort or dysphotopsia, and favorable Emotional Wellbeing (90.1 ± 16.9).
Conclusion
This large real-world series demonstrates that a nondiffractive wavefront-shaping Vivity IOL provides excellent distance acuity, functional near vision, precise refractive predictability, and low complication rate.