The Presbyopia Lens Ophthalmic Surgery Questionnaire (Plos-Q): Development And Validation
Published 2025 - 43rd Congress of the ESCRS
Reference: PP26.04 | Type: Free paper | DOI: 10.82333/zs2z-tn24
Authors: Zahra Javdani S. M.* 1 , Frank Goes 2 , Guido Van Hal 3 , Robert kuijpers 4 , Deborah Herrera 3 , Ismael Daoudi 5 , Helmut Molzahn 6
1ophthalmology,Joseph Bracops hospital,Brussels,Belgium, 2ophthalmology,Oogarts-Sion House,Braschaat,Belgium, 3Epidemiology,university Antwerp,Antwerp,Belgium, 4Ophthalmology,Albert Schweitzer Hospital Dordrecht,Dordrecht,Netherlands, 5Medicine,ULB,Brussels,Belgium, 6Anesthesiology,AZJP,Vilvoorde,Belgium
Purpose
To develop a standardized and validated electronic questionnaire, a patient-reported outcome measure (PROM), to collect health outcomes in clinical and registry studies on visual function, optical quality, quality of life and patient satisfaction after implantation of intraocular lenses with various designs for presbyopia-treatment.
Setting
Questionnaire development and validation study at the Department of Ophthalmology, Goethe University Clinic in Frankfurt, Germany.
Methods
The Presbyopia Lens Ophthalmic Surgery Questionnaire (PLOS-Q) was developed based on a literature and instrument review. Expert assessment was performed among 10 ophthalmologists, 5 optometrists and 3 clinical trial assistants specifically experienced in Intraocular lens (IOL) trials. A Pre-Test including patients after intraocular lens implantation was performed to ensure understandability and relevance of the questionnaire. Validity was tested analyzing the internal consistency of the PROM with Rasch analysis, factor analysis and the calculation of Cronbach’s alpha of a patient population including 156 patients after intraocular lens implantation. Reliability was assessed evaluating the test-retest reliability.
Results
The PLOS-Q includes quality of life subitems about spectacle independence and difficulties during daily activities at far, intermediate and near distance: reading a newspaper, price tags, on a mobile, the dashboard, housework, gardenwork, cinema/theater, watching TV, driving at daytime, driving at nighttime, reading a newspaper at dim light. Furthermore, the PLOS-Q investigates optical quality of vision subitems about the frequency, severity and bothersomeness of 6 optical phenomena: halo, starburst, glare, hazy vision, blurred vision and double vision. The PROM also assesses the subjective patient satisfaction after intraocular lens implantation.
Conclusions
The PLOS-Q is expected to be a fit-for-purpose PROM to collect health data on visual function, optical quality, quality of life and patient satisfaction after implantation of intraocular lenses with various designs for presbyopia-treatment. Results on validity will be presented. Using this instrument in registry studies on intraocular lens performance might help to improve intraocular lens selection for presbyopia treatment taking patients’ outcomes into account.