Canaloplasty Performed With The Itrack Microcatheter To Reduce Iop In Uncontrolled Glaucoma Eyes

To evaluate intraocular pressure (IOP) control and medications reduction in uncontrolled glaucoma eyes.

Multicenter, cloud-based database (iTDGR, part of International Glaucoma Surgery Registry - IGSR).

Eyes which received canaloplasty performed with an ab-interno approach with the iTrack microcatheter (Nova Eye Medical) and combined with phacoemulsification with a preoperative IOP above 18mmHg (defined as uncontrolled IOP) were included. Primary endpoints were IOP reduction, control of IOP equal or below 18mmHg, and medications reduction. Postop data was taken from the last observation.

88 eyes with a mean preoperative IOP (mmHg) of 23.0±5.2 and on 1.8±1.2 medications were recruited. Postop mean follow-up: 21.8±7.6 months. IOP and medications were reduced to 15.3±4.2 and 1.1±1.3 at postop (p<0.001). 83% of the eyes were controlled (equal or below 18 mmHg) at postop. Mean IOP decreased in 92% of the eyes, while the number of medications decreased in 54% of the eyes, stayed the same in 37%, and increased in 9% of the eyes. Potentially related adverse events were: hyphema >10% anterior chamber (1/88), and retinal detachment (1/88).

Canaloplasty performed via an ab-interno technique resulted in a significant reduction of IOP in uncontrolled glaucoma eyes. The majority of baseline uncontrolled glaucoma eyes were IOP controlled following the canaloplasty procedure.