Pseudophakic Eyes Implanted With Presbyopia-Correcting Iol Designs Analyzed By Pyramidal Aberrometry And Anterior Segment Oct
Published 2025 - 43rd Congress of the ESCRS
Reference: PP19.08 | Type: Free paper | DOI: 10.82333/nr3h-fy35
Authors: Jinhai Huang* 1 , Rui Ning 1 , Yiran Wang 1 , Ingemar Gustafsson 2 , Xingtao Zhou 1
1Fudan University,Shanghai,China, 2Lund University, Skåne University Hospital,Lund,Sweden
Purpose
To study and compare via pyramid wavefront sensing (PWS) and anterior segment optical coherence tomography (OCT) interrelated wavefront and biometric data following implantation of currently employed presbyopia-correcting intraocular lens (IOL) designs.
Setting
Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital, Vienna, Austria
Methods
180 eyes of 90 patients will be included, consisting of 9 different groups that were bilaterally implanted with monofocal, spherical-aberration modulating, extended depth-of-focus, refractive, and diffractive IOL designs: a) Acrysoft SN60WF, b) Acrysoft IQ Vivity, c) AT Lisa Tri, d) RayOne Trifocal, e) Tecnis Symphony ZXR00, f) Tecnis Eyhance ICB00, g) RayOne EMV, h) Acunex Varo AN6V, i) Tecnis PureSee. Clinical through-focus curves, defocus curves acquired by PWS, and defocus curves computed via synthetic wavefront data from biometric eye models are analyzed and compared. Additionally, mean point spread functions (PSFs) and Strehl ratios, root mean square (RMS) aberration error, as well as internal IOL optics, are compared.
Results
Preliminary data revealed that total RMS, PSF Strehl ratio, and internal IOL aberrations varied significantly between the study groups. The depth of field of spherical aberration-modulating IOLs was pupil-size dependent and dependent on inter-individual corneal aberrations. In eyes implanted with diffractive IOL optics, PWS-derived defocus curves were statistically significantly altered compared to the depth of field measured by clinical defocus curves and computed theoretical values.
Conclusions
Clinical image quality parameters as measured by PWS differed significantly between IOL designs. Interlinking perioperative biometric and aberrometric data with currently employed IOL designs can significantly increase the degree of sophistication for predicting depth of focus and its trade-off with contrast sensitivity deterioration in clinical practice. Nevertheless, when using near-infrared ocular wavefront sensing, the wavelength-dependence of diffractive IOLs prohibits an adequate reproduction of multifocal light intensity distribution under visible light, which requires simulations and adjustments in post-processing.