Six-Month Outcomes Of Cw Guided Prk For Keratoconus In 467 Eyes

This study aims to evaluate the six-month postoperative outcomes of corneal wavefront-guided photorefractive keratectomy (CW-guided PRK) in the treatment of keratoconus, based on data from 467 eyes. The primary objective of the procedure was to improve corneal stability and visual acuity by employing a personalized treatment protocol, utilizing precise wavefront-guided ablation patterns tailored to the individual topography and refractive characteristics of each patient's cornea.

This study evaluates six-month outcomes of CW-guided PRK in 467 eyes with stable keratoconus. The procedure aimed to improve corneal stability and visual acuity using individualized wavefront-guided ablation. Patients underwent PRK with the SchwindAmaris laser and simultaneous corneal cross-linking. Inclusion criteria: residual stromal thickness >300 microns and ablation depth ≤50 microns.

This prospective study included 467 eyes diagnosed with stable keratoconus. All patients underwent corneal wavefront-guided photorefractive keratectomy (CW-guided PRK) using the SchwindAmaris laser system. Treatment planning and execution were facilitated by Phenix and ORK CAM software to ensure individualized and precise ablation patterns based on each eye's topography and wavefront data. A simultaneous corneal cross-linking procedure was performed immediately after PRK to enhance corneal stability. Inclusion criteria: residual stromal thickness >300 microns and ablation depth ≤50 microns. Six-month postoperative outcomes were evaluated.

At six months, significant improvements were observed in corneal stability and visual acuity. Most patients experienced a reduction in corneal astigmatism and improved uncorrected visual acuity. The procedure maintained a high safety profile, with all treatments adhering to the required residual stromal thickness and ablation depth limits. Postoperative keratometry values remained within the desired range, contributing to enhanced visual outcomes and high patient satisfaction. No serious complications were reported.

CW-guided PRK, combined with corneal cross-linking, proves to be an effective and safe treatment for stable keratoconus, yielding promising six-month outcomes. The individualized approach enhances corneal stability and visual acuity. The method demonstrates a high safety profile, and the positive results support its use as a viable option for managing keratoconus. Personalized treatment plans, tailored to each patient's specific corneal condition, contribute to long-term visual improvement and patient satisfaction.