Allogeneic Anterior Lens Capsule Transplantation (Alct) For The Management Of Hsv Neurotrophic Keratitis
Published 2025 - 43rd Congress of the ESCRS
Reference: PP06.15 | Type: Poster | DOI: 10.82333/0f5e-gb44
Authors: Dionysios Vakalopoulos* 1 , Vasileios Tsagkogiannis 1 , Konstantina Togka 1 , Marios Katsimpras 1 , Marina Chatzea 1 , Lida Lalou 1 , George Kymionis 1
11st Department of Ophthalmology “G. Gennimatas” Hospital,National and Kapodistrian University of Athens,Athens,Greece
Purpose
To report a case of allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic epithelial keratitis.
Setting
The study was conducted at G. Gennimatas General Hospital, Athens, Greece. The patient received preoperative evaluations, surgical intervention, and follow-up examinations within a controlled clinical environment.
Methods
An 81-year-old man was referred to our department due to neurotrophic keratitis in the left eye that he had been suffering from over the past 3 months. He had recurrent episodes of HSV keratitis in the left eye over the past 3 years and despite multiple previous treatments, there was no improvement. At the time of presentation, corrected distance visual acuity was no light perception in the left eye. Slit-lamp examination revealed a corneal epithelial defect with underlying stromal thinning and concomitant scarring. An allogeneic anterior lens capsule (ALC) was placed over the epithelial defect to act as a biological dressing, anchored with a droplet of fibrin glue. A bandage contact lens was placed over to prevent the slippage of the ALC.
Results
No intra or postoperative complications were observed. Two weeks later, the ALC was removed revealing complete epithelial healing, while two months later the epithelium remained completely healed with a significant reduction of corneal scarring.
Conclusions
Anterior Lens Capsule transplantation (ALCT) seems to be a promising new treatment option for the management of corneal neurotrophic keratitis.