ESCRS - PP05.04 - Analysis Of Factors Influencing Postoperative Refractive Error After Cataract Surgery

Analysis Of Factors Influencing Postoperative Refractive Error After Cataract Surgery

Published 2025 - 43rd Congress of the ESCRS

Reference: PP05.04 | Type: Free paper | DOI: 10.82333/krbg-5115

Authors: Stefano Gallio* 1 , Rita Mencucci 1 , Marco Lombardo 2 , Mario Fruschelli 3 , Danilo Alunni Fegatelli 4

1Ophthalmology Unit,University of Florence, Careggi Hospital,Florence ,Italy, 2Studio Italiano di Oftalmologia,Rome,Italy, 3Ophthalmology Unit, Dip.Scienze mediche chirurgiche e neuroscienze,Policlinico Santa Maria alle Scotte, University of Siena,Siena,Italy, 4Department of Life Sciences, Health and Health Professions,Link Campus University,Rome,Italy

Purpose

To investigate the changes in refractive error one month after the implantation of non-astigmatism-correcting intraocular lenses(IOL) in cataract patients, based on age groups, gender differences, and different ocular parameter groups.

Setting

Retrospective cohort study

Methods

We obtained data from 1,125 cataract patients (1,651 eyes) who underwent implantation of non-astigmatism-correcting IOL at Wuhan Aier Eye Hospital from January 2023 to January 2025. The dataset included age, gender, preoperative ocular biometric parameters: axial length (AL), mean corneal curvature (Km), anterior chamber depth (ACD), lens thickness (LT), and postoperative one-month refractive error (RE). We used Pearson correlation analysis, one-way ANOVA, independent sample t-test, and linear regression analysis to investigate the distribution and changes in RE after cataract surgery across different parameters. We further constructed a multiple linear regression equation for postoperative RE using parameters with significant correlations.

Results

The mean RE (−0.1944±0.7094D) was found. RE showed weak positive correlations with AL (R=0.246) and ACD (R=0.194), but weak negative correlations with age (R= -0.120) and Km (R= -0.146), with no significant correlation with LT.  In subgroup analyses, for patients with long AL (≤26.5 mm), RE negatively correlated with increasing AL (p= 0.015), while for those with AL>26.5 mm, a positive correlation was found (p= 0.000).For patients with shallow anterior chambers (p=0.217) and abnormally high Km (p=0.008), RE  shifted towards myopia. However, as ACD increased, refractive error gradually shifted towards emmetropia (p=0.000). A multiple linear regression model: RE = 0.045×AL −0.038×Km + 0.339×ACD + 0.216×LT −1.605 (R²= 0.088, p= 0.000).

Conclusions

Based on our stratified analysis of demographic and ocular biometric parameters, we found that with increasing age, postoperative refractive error in cataract patients tends to shift towards myopia, and this myopic shift is more pronounced in patients with short axial length, shallow anterior chamber, or abnormally high corneal curvature. Conversely, in patients with extremely long axial length, increasing axial length leads to a greater hyperopic shift.

Keywords: cataract; refractive error; parameters; correlation.