ESCRS - PO982 - A Comprehensive Analysis Of Light And Thermal Therapy On Evaporative Dry Eye Disease

A Comprehensive Analysis Of Light And Thermal Therapy On Evaporative Dry Eye Disease

Published 2025 - 43rd Congress of the ESCRS

Reference: PO982 | Type: Poster | DOI: 10.82333/g4zp-bb53

Authors: Yu-Yin Lai* 1 , Chao-Kai Chang 2 , Mei-Yu Shen 3 , Wen-Chuan Kuo 4

1Institute of Biophotonics,National Yang Ming Chiao Tung University,Taipei,Taiwan, Province of China;Nobel Eye Institute,Taipei,Taiwan, Province of China, 2Nobel Eye Institute,Taipei,Taiwan, Province of China;Department of Optometry,Da-Yeh University,Changhua,Taiwan, Province of China, 3Statistics and Information Science,National Changhua University of Education,Changhua,Taiwan, Province of China, 4Institute of Biophotonics,National Yang Ming Chiao Tung University,Taipei,Taiwan, Province of China

Purpose

To compare the therapeutic effects of two treatment modalities, intense pulsed light (IPL) and thermal pulsation therapy (TPT), with conventional treatment methods, for treating meibomian gland dysfunction (MGD)-associated dry eye disease (DED).

Setting

A prospective randomized interventional study conducted in a specialized eye clinic.

Methods

Participants diagnosed with MGD-associated DED were allocated to the experimental group, which received IPL on one eye and TPT on the other eye, and the control group, which received conventional MGD treatment, including lubricants, anti-inflammatory eye drops and ointments. After the treatment period, both groups were re-evaluated for therapeutic effects.

Results

41 participants aged 45.4 ± 16.5 years old (30 female and 11 male) completed the study. The result showed more improvement in symptoms (Ocular Surface Disease Index score, P ≦ 0.001) and signs (tear meniscus height, lipid layer thickness) in the experimental group (P = 0.0024 and 0.03, respectively) than in the control group.

Conclusions

Both intense pulsed light (IPL) and thermal pulsation therapy (TPT) have shown superior therapeutic effects on meibomian gland dysfunction (MGD)-associated dry eye disease (DED) patients compared to conventional treatment.