ESCRS - PO968 - “Unveiling The Mystery: Steven Johnson Syndrome Presenting As Superficial Keratitis”

“Unveiling The Mystery: Steven Johnson Syndrome Presenting As Superficial Keratitis”

Published 2025 - 43rd Congress of the ESCRS

Reference: PO968 | Type: Poster | DOI: 10.82333/5yfm-eg34

Authors: Panagiota Freideriki Zora* 1

1Opthalmology,General Hospiral Of Nikaia,Peireus,Greece

Purpose

To describe a case of Steven Johnson Syndrome (SJS) diagnosed in a patient presenting with primary ocular findings.

Setting

“General Hospital of Nikaia”, Peiraias, Greece.

Methods

This is a case report of a patient presented at the Emergency Department of “General Hospital of Nikaia” and hospitalised at it. The data are collected from the patients medical records from the ED and her hospitalisation. Patients permission was granted for the conduct of this scientific report.

Results

A 65 year old female presented at the ED with a 2 day history of ocular and non specific viral prodromal symptoms in the context of 7 day history of tooth ache.She was receiving amoxicillin and lamotrigine p.os. She was hospitalised at the Internal Medicine department.The next day she suffered an allergic reaction and developed a blistering macular exanthema on her torso, face and neck. The patient was diagnosed with Steven Johnson Syndrome.She was found to have periorbital oedema, eyelid epidermal lesions, conjunctival membranes and pemphigoid OU. Both drugs were terminated, and she was started on the appropriate treatment protocols. She was evaluated daily for debridement of the membranes. 

Conclusions

Ophthalmologists may be the first physician to diagnose SJS, a life threatening condition that can initially present with non specific viral prodromal symptoms and ocular signs alone. This case emphasises the importance of considering a patients entire clinical history, especially when the presentation is atypical and the diagnosis is not obvious apparent.