Comparison Of Biomechanical Indices And Waveform-Derived Ocular Response Analyzer Parameters Across Different Refractive Error Groups
Published 2025 - 43rd Congress of the ESCRS
Reference: PO942 | Type: Poster | DOI: 10.82333/6qgc-9q35
Authors: Hatice Nur Nevruz Yılmaz* 1 , ONUR ÖZALP 2 , ERAY ATALAY 3
1OPHTHALMOLOGY,ESKISEHIROSMANGAZI UNIVERSITY,ESKISEHIR,Türkiye, 2OPHTHALMOLOGY,ESKISEHIR OSMANGAZI UNIVERSITY,ESKISEHIR,Türkiye, 3OPHTHALMOLOGY,eskisehirosmangazi university,eskişehir,Türkiye
Purpose
The aim of this study was to compare corneal hysteresis (CH), corneal resistance factor (CRF), and waveform-derived ocular response analyzer (ORA) parameters across different refractive error groups.
Setting
Eskişehir Osmangazi University, Eskişehir, Turkey.
Methods
This retrospective study included 32 eyes with hyperopia (spherical equivalent [SE] ≥ +0.50 diopter [D]), 337 eyes with emmetropia (SE > -0.50 D and < +0.50 D), 654 eyes with low myopia (SE ≤ -0.50 D and > -3.0 D), and 157 eyes with moderate–high myopia (SE ≤ -3.0 D). Axial length (AL) and corneal pachymetry values were obtained from optical biometry, and Scheimpflug corneal tomography, respectively. CH, CRF and thirty-seven parameters derived from the waveform signal obtained with ORA were analyzed. Kruskal-Wallis H test with Bonferroni correction and Pearson correlation were used for analyses. p < 0.05 was considered statistically significant.
Results
CH (p=0.002), CRF (p=0.02), p1area (p=0.03), p2area (p<0.001), w2 (p<0.001), h2 (p=0.02), p2area1 (p<0.001), w21 (p<0.001), and h21 (p=0.02) decreased, while path2 (p<0.001), and path21 (p=0.001) increased from hyperopia to moderate-high myopia. For CH, significant differences were found between moderate-to-high myopia group and hyperopia (p=0.005) and emmetropia (p=0.02) groups. CRF showed no significant pairwise differences. The most notable waveform parameter, p2area, showed significant differences in all pairs except emmetropia-hyperopia pair. Neither CH nor CRF correlated with SE in all groups. AL correlated with CH only in the low myopia group, while corneal thickness correlated positively with CH and CRF in all groups
Conclusions
Corneal biomechanics progressively weaken from hyperopia to moderate-high myopia. CH and CRF values demonstrated a significant correlation with corneal thickness but showed no association with AL or SE. Parameters derived from the second applanation signal of ORA showed significant differences across the refractive error groups.