ESCRS - PO649 - S There A Difference In The Corneal Biomechanics Of Glaucomatous Patients, Patients With Ocular Hypertension And Healthy Subjects?

S There A Difference In The Corneal Biomechanics Of Glaucomatous Patients, Patients With Ocular Hypertension And Healthy Subjects?

Published 2025 - 43rd Congress of the ESCRS

Reference: PO649 | Type: Free paper | DOI: 10.82333/x4dt-d680

Authors: Mohamed El Barkani* 1 , CHAIMAE KHODRISS 1 , HAMZA BENMOUSSA 1 , MERIEM EL BAHLOUL 1

1MOHAMMED VI UNIVERSITY HOSTPITAL,TANGIER,Morocco

Purpose

Compare bio-mechanically corrected intraocular pressure (IOPb) measured by the Corvis-ST with pachymetry- adjusted IOP measured by Goldmann applanation (IOP-GAT) in patients with primary open-angle glaucoma (POAG), ocular hypertension (OHT) and controls.
Comparing central pachymetry in patients with glaucoma, ocular hypertension and controls

Setting

Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide.
Thin central corneal thickness (CCT) and ocular tone have been identified as potential risk factors for POAG.

Methods

We conducted a prospective cross-sectional study between 3 groups, group 1 POAG, group 2 represented by patients with ocular hypertension without glaucoma involvement and group 3 represented by controls.
This study compared the IOP measured by CorVis-ST and IOP-GAT of the 3 groups, as well as their pachymetry.

Results

We counted a total of 74 eyes, 46% with GPAO, 16% with HTO and 38% controls. Median IOP-GAT was 16.30 mmHg in group 1, 21.2 mmHg in group 2 and 14.50 mmHg in controls (p=0.013), while b-IOP was lower than IOP-GAT in all 3 groups, with medians of 14.80 mmHg, 18 mmHg and 13.20 mmHg in groups 1, 2 and 3 respectively (p=0.045).

Our study showed that PAOG patients have thinner corneas than controls
We showed that b-IOP was lower than IOP-GAT, so the difference between IOP-GAT and b-IOP in our study must be related to the "adjusted factors" that b-IOP corrects, namely age, CCT and corneal biomechanics.

Conclusions

A better estimate of IOP (such as b-IOP) could help distinguish HTO patients at high risk of progressing to glaucoma from those whose IOP is only overestimated

b-IOP could be useful in cases with borderline normal intraocular pressure.