ESCRS - PO642 - The Effect Of The Hypertensive Phase On The Long-Term Outcomes Of Ahmed Glaucoma Valve Implantation

The Effect Of The Hypertensive Phase On The Long-Term Outcomes Of Ahmed Glaucoma Valve Implantation

Published 2025 - 43rd Congress of the ESCRS

Reference: PO642 | Type: Free paper | DOI: 10.82333/3s7e-7984

Authors: Mei Xin* 1 , Liuzhi Zeng 2 , Suju Liu 3 , Gang Luo 4

1Chengdu First People's Hospital,Chengdu,China;Eye School of Chengdu University of TCM,Chengdu,China, 2Chengdu First People's Hospital,Chengdu,China, 3Eye School of Chengdu University of TCM,Chengdu,China, 4Mass Eye and Ear,Boston,United States

Purpose

To investigate the long-term effect of hypertensive phase (HP) on the clinical outcomes of Ahmed glaucoma
valve (AGV) implantation.

Setting

General Eye Hospital, Tehran, Iran.

Methods

The records of patients with different etiologies of glaucoma who underwent AGV implantation with at least 3 years of follow-up were retrospectively reviewed. HP was defined as the IOP > 21 mm Hg during the first three months after surgery. The main outcome measure was cumulative success defined as 5 < IOP ≤ 21 mmHg and 20% reduction from the baseline with or without IOP lowering medications. Results that do not achieve cumulative success or undergo glaucoma reoperation during the follow-up period are considered failures. The secondary outcome measures were intraocular pressure (IOP) and the number of glaucoma medications.

Results

A total of 120 patients (28 patients of HP, 92 patients without HP) with an average age (± SD) of
48.9 ± 19.6 years and a mean follow-up of 4.5 ± 1.4 years were enrolled. The mean duration of survival was 5.3 ± 0.5 years
in HP which was significantly shorter than 6.4 ± 0.2 years in non-HP (log rank = 4.2, P = 0.04). Mean IOP and number of
IOP lowering agents were higher in postoperative visits at 1,2, 3, and 4 years in HP patients compared with non-HP (all
Ps < 0.01). Higher baseline IOP was significantly associated with higher rates of surgical failure.

Conclusions

In the long-term follow-up, the duration of survival was significantly longer in the non-HP group. In the non-
HP group, the failure rate was significantly lower than the HP group.