ESCRS - PO580 - Evaluation Of Corneal Biomechanic, Aberrometric And Topographic Parameters In Patients With High Superior-Inferior Corneal Asymmetry

Evaluation Of Corneal Biomechanic, Aberrometric And Topographic Parameters In Patients With High Superior-Inferior Corneal Asymmetry

Published 2025 - 43rd Congress of the ESCRS

Reference: PO580 | Type: Free paper | DOI: 10.82333/vy3q-1f89

Authors: Saleh Al Obeidan* 1 , Ahmed Mousa 2 , Faisal Almobarak 1 , Abdulsalam Al Turjoman 1 , Essam Osman 1 , Abdulaziz Al Arefi 1 , Ehab AlSirhy 1 , Philippe Kestelyn 3

1Ophthalmology,King Saud University,Riyadh,Saudi Arabia, 2Research Department,King Khaled Eye Specialist Hospital,Riyadh,Saudi Arabia, 3Ophthalmology,Ghent University,Gent,Belgium

Purpose

To evaluate the correlation between corneal biomechanic, aberrometric and topographic parameters in patients with high superior-inferior corneal asymmetry.

Setting

Oftalmosalud Institute, Lima, Peru.

Methods

We included 44 eyes of 32 patients with superior-inferior asymmetry > 1.5 D between February to December 2024.  Patients with previous ocular surgery were excluded. Refractive, tomographic (Oculus Pentacam), biomechanical parameters (Corvis ST), epithelial thickness (Schwind MS-39) were measured.

Results

Forty-four eyes of 32 patients with an average age of 28.6 ± 11.78 years (11 – 57 years).  Mean spherical equivalent -1.75 ± -2.65 D (-11.00 D – 3.13 D), mean Kmax 46.5 ± 1.84D (43.18 - 50.53D), while thinnest pachymetry mean value was 550.62 ± 41.84 µm (446 - 633 µm).  BAD-D values of 1.42 ± 0.61, CBI 0.26 ± 0.22 (0 - 0.92) and TBI 0.24 ± 0.27 (0 - 0.92).  Mean values for vertical coma were 0.424 ± 0.147 (0.061 - 0.779) and epithelial thickness 51.69 ± 2.5 µm (44.9 - 56.8 µm).  No significant correlation was found between variables, except for BAD D (rho= 0.353, p= 0.017) and vertical coma (rho= 0.375, p= 0.011).  

Conclusions

Patients studied with superior-inferior asymmetry > 1.5 D typically have mild hyperopia with high astigmatism.  Kmax, pachymetry and corneal biomechanics do not show patterns compatible with corneal ectasi.  Nevertheless, the correlation between BAD-D and vertical coma with superior-inferior asymmetry suggests its refractive impact without altering corneal structure.