Preclinical Analysis Of A New Biaspheric, Phase-Ring Based, Enhanced Monofocal Iol

Published 2025 - 43rd Congress of the ESCRS

Reference: PO375 | Type: Free paper | DOI: 10.82333/jv4m-ca73

Authors: Christoph Spartalis* ¹ , Manuel Ruiss ¹ , Johannes Zeilinger ¹ , Natascha Bayer ¹ , Caroline Pillwachs ¹ , Oliver Findl ¹

¹Vienna Institute for Research in Ocular Surgery,Vienna,Austria

Purpose

To compare the optical quality and visual performance of the Asqelio™ Pluris™ enhanced monofocal intraocular lens (IOL), featuring Phase-Ring technology, against the Asqelio™ monofocal IOL through optical bench analysis under various lighting conditions.

Setting

University of Valencia

Methods

A laboratory optical bench study was conducted to evaluate the through-focus modulation transfer function (MTF) and defocus curves of the Asqelio™ Pluris™ enhanced monofocal and Asqelio™ monofocal IOLs. Lenses were tested in a water-filled optical tray under photopic, mesopic, and scotopic conditions with apertures of 2.0 mm, 3.0 mm, and 4.5 mm. Image quality was assessed using a USAF resolution target across a diopter range from -1.0 D to +4.0 D.

Results

The Asqelio™ Pluris™ enhanced monofocal IOL demonstrated a superior intermediate-range performance compared to the monofocal counterpart, as evidenced by enhanced MTF values and a smoother computed defocus curve. At 3.0 mm pupil size, Pluris™ exhibited a broader depth of focus, maintaining better optical quality at intermediate distances without compromising distance vision. The Phase-Ring technology provided sharper image resolution across defocus levels while minimizing spherical aberrations. Additionally, the Pluris™ lens shows thinner central thickness, which may facilitate smaller surgical incisions.

Conclusions

Optical bench testing indicates that the Phase-Ring enhancement implemented in the Asqelio™ Pluris™ enhanced monofocal IOL significantly improves intermediate-range optical performance compared to a standard monofocal IOL. This technology offers a wider functional range without inducing photic phenomena, potentially reducing patient dependence on additional optical correction. Further clinical validation is required to confirm these advantages in vivo.