Effect Of Corneal Biomechanical Properties Measured By Corvis St On Postoperative Implantable Collamer Lens (Icl) Vault
Published 2025 - 43rd Congress of the ESCRS
Reference: PO1062 | Type: Poster | DOI: 10.82333/qjrf-tx75
Authors: Ramin Salouti* 1 , Mostafa Nazarpour-Servak 1 , Kia Salouti 2 , Maryam Ghoreyshi 3 , M. Hossein Nowroozzadeh 1
1Ophthalmology Department,Shiraz University of Medical Sciences,Shiraz,Iran, Islamic Republic Of, 2Science Department,The University of British Columbia,Vancouver,Canada, 3Salouti Eye Clinic, Salouti Cornea Research Center,Shiraz,Iran, Islamic Republic Of
Purpose
To evaluate the impact of corneal biomechanical parameters, measured by Corvis ST, on postoperative Implantable Collamer Lens (ICL) vault.
Setting
Salouti Eye Clinic.
Methods
A retrospective analysis of 75 participants (mean age: 31.0 ± 5.1 years) who underwent ICL implantation was conducted. Data from both eyes were analyzed separately to minimize the risk of Type I statistical error. Corneal biomechanical indices, including applanation times, deflection amplitudes, and stiffness parameters, were assessed using multiple linear regression and logistic regression analyses.
Results
Logistic regression analysis revealed delta (OR:73.7, 95% CI:2.0–2759.2, p=0.020) as the sole predictor of high vault (>750 µm) in right eyes. In left eyes, delta (OR:143.8, 95% CI:1.9–11,056.4, p=0.025) and A2 time (OR:0.206, 95% CI:0.047–0.914, p=0.038) were predictors of high vault. For low vault prediction, ARTh (OR:0.982, 95% CI:0.970–0.995, p=0.007) and delta (OR:0.017, 95% CI:0.001–0.342, p=0.008) were the only independent biomarkers for right and left eyes, respectively. Eyes with ARTh values greater than 400 had a 9.3-fold higher odds (95% CI:2.5–34.1; p=0.001) of developing low postoperative ICL vaults compared to eyes with ARTh ≤400. This finding was confirmed by left eye data (OR:3.2; 95% CI:0.98–10.1; p=0.053).
Conclusions
While corneal biomechanical parameters such as A2 time, CBI, and ARTh significantly influence ICL vault, delta was identified as the most important predictor. These findings highlight the potential of combining prediction error with biomechanical profiling to optimize ICL sizing and improve postoperative outcomes. We also hypothesize that incorporating intermediate ICL sizes may further enhance vault predictability and increase the clinical relevance of biomechanical parameters.
Conflict of Interest: None of the authors has any conflict of interest with the material discussed in this study.
Financial support: No funding.