Posterior Continuous Curvilinear Capsulorrhexis For Posterior Capsule Opacification And Intraocular Lens Stability In Highly Myopic Eyes: A Randomized Clinical Trial
Published 2025 - 43rd Congress of the ESCRS
Reference: FP28.02 | Type: Free paper | DOI: 10.82333/v0g9-4h07
Authors: Fatma Feyza Nur Keskin Perk* 1 , Cafer Tanrıverdi 2 , Aylin Kılıç 3
1Diyadin State Hospital,Ağrı,Türkiye, 2Dünyagöz Hastanesi,İstanbul,Türkiye, 3Swiss Vision Clinic,İstanbul,Türkiye
Purpose
Primary posterior continuous curvilinear capsulorrhexis (PCCC) can reduce posterior capsule opacification (PCO) and achieve better intraocular lens (IOL) stability after cataract surgery. However, it remains unknown whether PCCC is effective in PCO prevention and influences IOL stability in highly myopic eyes. This study is conducted to evaluate the influence of PCCC on PCO development and IOL stability (decentration, tilt, axial shift, and rotation) in highly myopic eyes.
Setting
This randomized intraindividual clinical trial was conducted between June 2023 and January 2025 at the Fuzhou University Affiliated Provincial Hospital, Fuzhou, China.
Methods
Patients with bilateral cataract and an axial length (AL) of 26 mm or longer were enrolled, with one eye randomly assigned to the PCCC group (phacoemulsification cataract surgery combined with PCCC) and the contralateral eye to the control group (without PCCC). IOL decentration, tilt, anterior chamber depth (ACD) were evaluated using Scheimpflug anterior segment imaging device. PCO and axis orientation were measured using retroillumination photos after pupil dilation. Patients were examined at 1 day, 1 week, 1 month, 3 months, 6 months, and 1 year after cataract surgery.
Results
A total of 60 eyes from 30 participants were enrolled, with 56 eyes from 28 participants completing the 1-year follow-up. In the control group, 2 eyes exhibited PCO in the central 3-mm diameter area, while no eyes in the PCCC group showed this (p = 0.002, Fisher's Exact Test). The PCCC group demonstrated a smaller change in ACD from postoperative day 1 to 1 year (0.079 mm vs. 0.131 mm; P = 0.006). Additionally, the PCCC group exhibited smaller IOL decentration (0.214 mm vs. 0.249 mm; P = 0.372) and tilt (2.353° vs. 2.511°; P = 0.623) at 1 year, although these differences were not statistically significant. No rotational differences were observed between the PCCC and control group.
Conclusions
PCCC reduced PCO and IOL axial shift in eyes with an AL of 26 mm or longer. These findings support the use of PCCC in these eyes.