Defocus Curve Analysis Of New Full Range Of Vision Iol With Spiral Optic Designed With Artificial Intelligence

This analysis aims to present the range of vision extension in clinical defocus curve analysis with the novel spiral full range of vision intraocular lens (IOL). According to the manufacturer a proprietary AI engine created a unique optical spiral tuned for optimal patient outcomes. Spiral tracks allow continuous variance of power, focusing light at every position along the defocus curve producing a smooth and continuous full range of vision.

Multicentre data collection:

• ADVALIA Vision, Milan, Italy
• Department of Ophthalmology and Optometry at Medical University of Vienna, Vienna, Austria
• Department of Ophthalmology at University Eye Clinic Heidelberg, Germany
• OCL Vision, London, England
• Auckland Eye, Auckland, New Zealand
• Clínica Privada de Oftalmologia, Lisbon, Portugal
• Clinica Baviera Aier Group, Valencia, Spain
• Vision Scotland, Edinburgh, Scotland
• Rothschild Foundation Hospital, Paris, France

Preoperatively, a slit lamp examination, keratometry and biometry, as well as subjective refraction was performed. The follow-up visit was scheduled for one month and three months after surgery and monocular and binocular corrected defocus curve measurements were performed in half dioptre steps from +1.0 D to -4.0 D.

At one month post op total of 91 patients (182 eyes) were operated, of which 57 patients were available for analysis at 1-month and 25 patients at 3-month follow-up. At 1 month and at 3 months post-op the monocular and binocular corrected defocus curves showed a peak at 0 (distance) with a mean visual acuity (VA) of -0.02±0.08, 0.00±0.08, -0.04±0.08 and -0.06±0.12 logMAR, respectively. At -1.5 D defocus (~66 cm) the mean VA were 0.08±0.11, 0.08±0.08, 0.03±0.09, and 0.02±0.06 logMAR, respectively. At a defocus of -3.0 D (~33 cm) the mean VA were 0.33±0.13, 0.32±0.14, 0.24±0.13, and 0.24±0.13 logMAR, respectively. A VA of 0.2 logMAR or better was achieved from +1.0 D to -2.75 D.

Monocular and binocular defocus curves showed stable defocus patterns at 1-month and 3-month follow-ups. The binocular defocus curve showed a full range of vision extension, with a smooth plateau from +0.5 D to -2.5 D, and VA of 0.2 logMAR or better across a ~4.0 D range. No dip was observed in intermediate vision on the defocus curve, contrasting with the wave-like defocus pattern typically seen in trifocal IOLs, where VA drops at the intermediate distances. The results demonstrate that the novel full range of vision IOL featuring a unique spiral design provides a smooth and continuous defocus curve from far to near distances. These findings suggest that patients can reach a high level of spectacle independence.