Comparison Of Optical Performance With An Artificial Designed Spiral Intraocular Lens And A Trifocal Iol

The aim of this study was to compare an IOL with spiral optics (RayOne Galaxy) developed with AI (artificial intelligence) with a diffractive trifocal IOL (RayOne Trifocal) in terms of quality of vision and subjective preference.

Single-centre, prospective double-blinded study at the Department of Ophthalmology, Hospital St. John, Vienna.

Thirty healthy subjects aged 18-40 participated in this preclinical, double-blind study comparing the visual performance of two IOLs. A Real Artificial Lens Vision (RALV) device (Dezimal GmbH) was employed under cycloplegia to simulate monocular, postoperative vision in the dominant eye. Distance, near, and intermediate visual acuity, as well as glare sensitivity and contrast sensitivity, were measured. A defocus curve was generated for each IOL, and subjective preference was also assessed.

Clinical data demonstrated a statistically significant advantage in intermediate visual acuity (p=0.005) for spiral optics IOL compared to a diffractive trifocal IOL, without any decrement in near or distance vision. Spiral Optics IOL also yielded statistically significant reductions in glare (p=0.00001) and improvements in contrast sensitivity (p=0.051). In a direct subjective comparison, 90% of patients preferred the Galaxy IOL for near vision.

Our findings indicate that the spiral optics IOL presents a promising alternative to diffractive IOLs. This evaluation utilized a controlled optical system to assess IOL performance, removing the complexities of individual patient variations and surgical factors. The analysis revealed excellent intermediate visual acuity, coupled with improvements in contrast sensitivity and a reduction in visual disturbances for the spiral optics IOL. Simulated patient preference leaned strongly towards spiral optics IOL. While these results are encouraging, further clinical investigations are necessary to validate these findings.