Assessment Of Axial Stability Of Widely Implanted Monofocal Intraocular Lenses In A Human Capsule Computational Model
Published 2025 - 43rd Congress of the ESCRS
Reference: FP01.07 | Type: Free paper | DOI: 10.82333/m4fw-hp57
Authors: Magdaléna Vokrojová* 1 , Věra Trnková 2 , Lenka Havlíčková 2 , Zuzana Hlinomazová 2
1Lexum Eye Clinics (Optegra Group),Prague and Brno,Czech Republic;3rd Faculty of Medicine,Charles University,Prague,Czech Republic, 2Lexum Eye Clinics (Optegra Group),Prague and Brno,Czech Republic
Purpose
It is known to the ophthalmic community that intraocular lenses (IOLs) can move axially post implant. There is publication that demonstrates axial movement in compression test cell. The purpose of this study is to evaluate the impact of haptic and capsule geometry on the axial stability of widely used monofocal intraocular lenes (IOLs) in a human eye capsule computational model.
Setting
This analytical study is based on the human eye capsule computational model at Alcon Research, Fort Worth, Texas, USA.
Methods
Human capsule model was developed based on the clinical data to mimic the human eye physiology. Axial stability of Alcon Acrysof SN60WF and Clareon CNA0T0, JnJ Tecnis ZCB00, Zeiss CT Lucia 601PY, B&L enVista MX60, Santen Eternity W-60 and Hoya Vivinex XY1 was previously studied based on the benchtop ISO 11979 compression rigid cell test data. However, the interaction an IOL has with the soft and membrane-like human eye capsule model is expected to be different and such data will better inform clinical decision-making. Therefore, the axial stability of the above IOLs was studied in a human eye capsule computational model developed at Alcon to better understand the impact of haptic and capsule geometry on IOL axial stability.
Results
We have evaluated the axial stability in various capsule sizes. Results compared favorably with the bench test data and demonstrated that CNA0T0 is the most stable IOL geometry in the median capsule with a posterior movement of 94 µm. ZCB00 has the largest axial movement of 190 µm among the studied IOLs.
Conclusions
In this study, we successfully compared the axial stability of different monofocal IOLs in various sized capsules. Our results demonstrated that the axial stability of the IOL is sensitive to changes in haptic and capsule geometry.