Efficacy Of Ab-Interno Canaloplasty With The Itrack Performed With And Without Gatt Following Previous Glaucoma Laser Treatment

To investigate the clinical outcomes of ab-interno canaloplasty with iTrack microcatheter  (Nova Eye Inc) with and without GATT in eyes with no previous glaucoma surgery (selective laser trabeculoplasty or SLT; diode cyclophotocoagulation or CPC) and in eyes with previous SLT or CPC over a 12-month period.

Retrospective single center, single surgeon

This was a non-randomized, single center, single surgeon, retrospective case series of eyes with uncontrolled primary open-angle glaucoma, who underwent either ABiC or ABiC+GATT. Eyes with no previous surgery (ABiC group) were compared to eyes with previous SLT or CPC laser treatment (ABiC+Laser group). Outcome measures include intraocular pressure (IOP) and number of glaucoma medications at 12 months postoperatively.

20 eyes (14 ABiC and 6 ABiC+Laser) of 12 patients (mean age: 71.2±6.6) were included. Mean baseline IOP and number of medications was 23.2±6.1 mmHg and 2.1±0.9 in the ABiC group and 19.8±2.3 mmHg and 2±0.9 in the ABiC+Laser group. At 12 months, mean IOP was under control in all eyes and reduced to 12.9±2.6 mmHg and 12.6±0.9 mmHg, respectively (p<0.005); the number of medications was reduced to 1.4±0.7 and 1.2±1.1, respectively (p>0.005). At 12 months postoperatively, there was no significant IOP or medications difference between the 2 groups (p>0.005). No adverse events were recorded.

ABiC results in a significant and comparable reduction in mean IOP in eyes with or without previous glaucoma laser treatment. When SLT or CPC are not able to control IOP, ABiC is an effective additional treatment with a high safety profile