Extended Depth Of Focus Versus Trifocal For Intraocular Lens Implantation: An Updated Systematic Review And Meta-Analysis
Published 2023 - 41st Congress of the ESCRS
Reference: PP05.03 | DOI: 10.82333/v7ef-3v31
Authors: Mohammad Karam 1 , Nahlaa Alkhowaiter 2 , Ali Alkhabbaz 3 , Ahmed Aldubaikhi 4 , Abdulmalik Alsaif 5 , Eiman Shareef 1 , Rnad Alazaz 6 , Abdulaziz Alotaibi* 1 , Mona Koaik 7 , Samir Jabbour 8
1AlBahar Ophthalmology Center,Kuwait,Kuwait, 2College of Medicine, King Saud bin Abdulaziz University for Health Sciences,Riyadh,Saudi Arabia, 3Faculty of medicine, Kuwait university ,Kuwait,Kuwait, 4Department of Radiology, King Faisal Specialist Hospital and Research Center,Riyadh,Saudi Arabia, 5Walsall Healthcare NHS Trust,West Midlands,United Kingdom, 6King Khaled Eye Specialist Hospital (KKESH),Riyadh,Saudi Arabia, 7Cornea, Anterior Segment and Refractive Surgery,University of Ottawa Eye Institute,Ottawa,Canada, 8Ophthalmology,Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal (CHUM),Montréal,Canada
To compare the outcomes of extended depth of focus (EDOF) versus trifocal intraocular lenses (IOLs)
in patients undergoing cataract surgery.
Systematic review and meta-analysis.
A systematic review and meta-analysis were performed as per the Preferred Reporting Items for
Systematic Reviews and Meta-analyses (PRISMA) Guidelines and a search of electronic information
was conducted to identify all comparative studies of EDOF versus trifocal lenses were included.
Postoperative refraction and visual acuity were primary outcome measures. Secondary outcome
measures included postoperative defocus curves, intraocular aberrations, contrast sensitivity (CS),
quality of vision (QoV) questionnaire score, haloes and glare, spectacle independence and patient
satisfaction. Fixed and random effects models were used for the analysis.
A total of 22 studies enrolling 2200 eyes were identified. Trifocal IOL showed a significant improvement in sphere and spherical equivalence (MD=-0.11, P=0.0001) compared to EDOF IOL. Trifocal IOL had superior near visual acuity outcomes, namely uncorrected near visual acuity (MD=0.12, P<0.00001) and distance-corrected near visual acuity (MD=0.12, P=0.002). Postoperative corrected distance visual acuity was significantly improved for the EDOF group. Defocus curve favoured trifocal IOLs at near vision and EDOF IOLs at intermediate vision. Ocular aberration, CS, haloes, glare and patient satisfaction were not statistically significant between the groups. Trifocal IOL had improved QoV questionnaire score and spectacle independence .
The trifocal IOLs have improved uncorrected near visual acuity compared to EDOF IOLs. Uncorrected distance and intermediate visual acuity, halos and glare are not statistically different between both groups.