ESCRS - PP03.05 - Comparison Of Mean Age And The Cataract Type Prevalence In The Cataract Onset In Patients With Previous Refractive Laser Refractive Surgery (Lasik).

Comparison Of Mean Age And The Cataract Type Prevalence In The Cataract Onset In Patients With Previous Refractive Laser Refractive Surgery (Lasik).

Published 2023 - 41st Congress of the ESCRS

Reference: PP03.05 | DOI: 10.82333/xjkf-am46

Authors: Celeste Briceno Lopez 1 , Neus Burguera-Giménez 2 , Mª Carmen García-Domene 3 , Mª Amparo Díez-Ajenjo 3 , Mª José Luque-Cobija 4 , Cristina Peris-Martínez* 5

1Research,FISABIO Medical Ophthalmology,Valencia,Spain;Research,UVEG-Alcon Cathedra,Valencia,Spain;Optics, Optometry, and Visual Sciences,University of Valencia,Valencia,Spain, 2Research,FISABIO Medical Ophthalmology,Valencia,Spain;Optics, Optometry, and Visual Sciences,University of Valencia,Valencia,Spain, 3Optics, Optometry, and Visual Sciences,University of Valencia,Valencia,Spain, 4Optics, Optometry, and Visual Sciences,University of Valencia,Valencia,Spain;Research,FISABIO Medical Ophthalmology,Valencia,Spain;Research,UVEG-Alcon Cathedra,Valencia,Spain, 5Surgery and Anterior Segment,FISABIO Medical Ophthalmology,Valencia,Spain;Medicine Department,University of Valencia,Valencia,Spain

To compare the mean age and cataract type prevalence at cataract onset between patients with and without previous Laser in Situ Keratomileusis (LASIK).

UVEG Cátedra Alcon- Universitat de València. FISABIO Ophthalmology Medical Center.

This prospective comparative study enrolled 314 patients (control group=244 eyes, LASIK group=70 eyes) with senile cataracts from the FISABIO Ophthalmology Medical Center (FOM). Both groups underwent manual phacoemulsification. Ocular and systemic pathological conditions were excluded from the study. Corneal thickness (CT) were measured with the Nidek CEM-530 (Nidek Co., Ltd.; Japan). Cataract classification (CC) was determined by an ophthalmologist. Spherical, irregular astigmatism, and wavefront aberrations (WFAZ40, WFAHOA, and WFA4mm) were measured using Pentacam® (Oculus Optikgeräte GmbH, Wetzlar, Germany). Vectorial components of refraction (M, J0, and J45), and visual acuity (BCVA), were measured before and 1 month after surgery.

The variables compared in the analysis were age, endothelial cell density, CT, CC, WFAZ40, WFAHO, and WFA4mm before phacoemulsification. M, J0, J45, and BCVA median were compared before and after surgery. The samples had a non-parametric distribution (Kolmogorov-Smirnov normality test, p<.01). U Mann-Whitney’s test for independent samples revealed significant differences between both groups before surgery in the age (z=7.996, p<.001), CT (z=3.665, p<.001), WFAHO (z=-3.981, p<.001) and WFA(z=-7.971, p<.001). A chi-square test revealed a link between ametropia and CC (z=13.534, p=.759). Refractive analyses revealed significant differences in MPRE (z=3.644, p<.001) and MPOST(z=2.118, p=.029).

Previous research(1-3) suggests that LASIK may cause cataracts to develop prematurely due to higher AXLs and ablation(4-6). Results show a significant difference in the mean age of both samples. Wavefront aberration analysis revealed that spherical and HOAs are higher in post-LASIK patients, significant for the second only.(7,8) On the contrary, corneal astigmatism was lower in LASIK patients due to the ablation and consequent corneal flattening. Furthermore, a link between ametropia and cataract type, most likely corticonuclear for all ametropias, was found. (2) Finally, refraction was more negative in the LASIK group, which can be due to the miscalculation of the IOL and changes in the refractive index after LASIK.(1,10)