ESCRS - PO1029 - Comparing The Clinical Outcome Of Transepithelial And Conventional Photorefractive Keratectomy In Correction Of Moderate Myopia: A Randomized Case Control Study

Comparing The Clinical Outcome Of Transepithelial And Conventional Photorefractive Keratectomy In Correction Of Moderate Myopia: A Randomized Case Control Study

Published 2023 - 41st Congress of the ESCRS

Reference: PO1029 | DOI: 10.82333/9w3g-xn94

Authors: Nader Nassiri* 1 , Kourosh Sheibani 2 , Sara Kavousnezhad 3

1Ophthalmology,Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences,Tehran,Iran, Islamic Republic Of, 2Basir Eye Health Research Center,Tehran,Iran, Islamic Republic Of, 3Vanak Eye Surgery Center,Tehran,Iran, Islamic Republic Of

To compare the clinical outcome of one-step transepithelial photorefractive keratectomy (tPRK) and conventional photorefractive keratectomy (PRK).

Vanak Ophthalmology Clinic, Tehran, Iran.

Consecutive patients with moderate myopia were randomly assigned to be operated either with tPRK or the conventional PRK method. The one-step tPRK and conventional PRK were both performed using the Schwind Amaris excimer laser system. Outcome measures included patients' one and three months post surgical uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), sphere, cylinder, spherical equivalent (SE), intraocular pressure, haze, contrast sensitivity, pain and discomfort.

In total 120 eyes from 60 consecutive patients were evaluated from May to December 2020. The mean UCVA, BCVA or SE did not show a statistically significant difference one and three months postoperatively. The mean haze among patients undergoing tPRK was significantly lower than the PRK group one month postoperatively (p < 0.001), but no difference was observed three months postoperatively. Patients undergoing tPRK experienced less pain (p = 0.027) and discomfort (p < 0.001) one day postoperatively. There was no difference between the two groups regarding postoperative intraocular pressure and contrast sensitivity.

Our study results suggest that the tPRK method is associated with less early postoperative pain and discomfort at day one and corneal haze at one month postoperatively compared to the conventional PRK method.