Rejuvenation Of Visual Age Utilizing A Novel Microporation Therapy To Uncrosslink The Sclera
Published 2023 - 41st Congress of the ESCRS
Reference: PO1009 | Type: Free paper | DOI: 10.82333/33wx-k581
Authors: Elizabeth Yeu* 1 , AnnMarie Hipsley 2 , Mitch Jackson 3 , Robert Ang 4
1Ophthalmology,Virginia Eye Consultants,Norfolk,United States, 2Ophthalmology,AceVision Group,Silver Lake,United States, 3Ophthalmology,JacksonEye,Lake Villa,United States, 4Ophthalmology,Asian Eye Institute,Makati City,Philippines
Purpose
To evaluate the impact of Dynamic Range of Focus loss in a presbyopic population upon visual age. To analyze effects of uncrosslinking ocular rigidity using a novel laser microporation therapy on halting or decreasing rate of progression of presbyopia.
Setting
Asian Eye Institute, Makati City, Philippines
Methods
The effect of uncrosslinking ocular rigidity using Laser Scleral Microporation (LSM) upon the visual age and rate of presbyopia progression was investigated. 100 eyes of 50 emmetropic presbyopes meeting inclusion criteria for an IRB Registered pilot study received LSM and were followed up to 12 months. DRoF recovery for near was measured using ETDRS cards at 40cm. DCNVA values were plotted over calendar age to express Visual Age (Old vs. Rejuvenated). Evaluation of calendar years of restored visual age after LSM was performed.
Results
Recovery of depth of focus was demonstrated by an improvement of DCNVA from logMAR 0.49±0.14 at baseline to 0.21±0.17, 0.23±0.16, 0.22±0.15, and 0.27±0.12 at 1, 3, 6, and 12 months (P<0.0001 for all). Visual age was calculated with the following equation: Age = (DCNVA + 0.455)/0.014. Baseline visual age of 67.2±10.1 years improved to 47.5±12.4, 49.3±11.2, 48.3±11.0, and 51.9±8.8 at 1, 3, 6, and 12 months respectively (P<0.0001 at all timepoints). Average change in baseline visual age was 18.7±11.4, 17.6±12.0, 18.0±12.3, and 15.4±12.2 years at 1, 3, 6, and 12 months after LSM (P<0.0001 for all). No complications in surgery or post-operative course were noted.
Conclusions
Visual Age may describe the effect of aging on the visual system. LSM appears to recover approximately 17.5±11.9 years of visual age (P<0.0001) in presbyopes with stability over 12 months. Further data collection will allow investigation into sustainability for up to 24 months.