ESCRS - PO0996 - Long-Term Safety Of V4c Posterior Chamber Intraocular Lens Implantation For The Correction Of Myopia In China

Long-Term Safety Of V4c Posterior Chamber Intraocular Lens Implantation For The Correction Of Myopia In China

Published 2023 - 41st Congress of the ESCRS

Reference: PO0996 | DOI: 10.82333/35ke-c445

Authors: Yuexi Chen* 1 , Qizhi Zhou 2 , Zheng Wang 1

1Refractive Surgery,Aier Eye Hospital, Jinan University,Guangzhou,China, 2Refractive Surgery, Chongqing Eye and Vision Care Hospital, Chongqing,China

To observe the long-term safety of V4c posterior chamber intraocular lens implantation (ICL V4c) for the correction of myopia in China over 5 years.

With the increasing prevalence of myopia in the world, the demand for myopia correction is increasing. Implantable posterior chamber intraocular lens (ICL), as an intraocular refractive surgery, is mainly used to correct high myopia, which provides a new way for the treatment of refractive errors other than corneal surgery. Nowadays, the long-term clinical efficacy, safety, complications after ICL  have become increasingly concerned by clinicians and patients.

A retrospective study. Patients from Chongqing Aier Eye Hospital with complete 5-year or more follow up were selected which underwent ICL V4c surgery in 2015. The uncorrected distant visual acuity(UCVA), best corrected visual acuity(BCVA), spherical equivalent (SE), intraocular pressure(IOP), corneal endothelial cell density (ECD), axis length (AL), vault, anterior chamber parameters and complications were recorded before and after surgery. A paired t test, Wilcoxon signed rank test and Pearson correlation were used for statistical analysis.

A total of 38 eyes from 20 patients were selected. The average follow-up time was (52.4 ± 5.2) months after operation. Before the ICL, the UCVA was 1.37 ± 0.26, the BCVA was 0.03 ± 0.05, and the SE was (-10.74 ± 2.74) D. At the last visit, the safety index is 1.21 ± 0.19, and the effective index is 0.85 ± 0.29; the mean vaults was (424 ± 250) um (range, 14um to1060um). The results of the last visit compared with those before operation: the UCVA increased and the BCVA was better, the difference was statistically significant (t = 27.63, 5.761, P < 0.001). There was no significant difference in IOP or AL (t = 1.737, 5.761, P > 0.05). The ECD decreased by an average of 4.5%. No serious complications were observed.

In 5 years of follow-up, the ICL V4c demonstrated high safety and satisfaction in myopic correction.