ESCRS - PO0605 - Efficacy Of Implantable Collamer Lens After Corneal Cross-Linking In Patients With Keratoconus

Efficacy Of Implantable Collamer Lens After Corneal Cross-Linking In Patients With Keratoconus

Published 2023 - 41st Congress of the ESCRS

Reference: PO0605 | DOI: 10.82333/txmr-f528

Authors: Akram Fekry Elgazzar* 1 , Ahmed Abdelaziz 2 , Walid Shaban Abdella 1 , Sewar Elejla 3 , Mariam Mohamed Ahmed 4 , Mohamed Abdelmonem Kamel 5 , Esraa Qobeia 6 , Sherein Diab 7

1Department of Opthalmology ,Faculty of Medicine, Al-Azhar University,Damietta,Egypt, 2Faculty of Medicine, Al-Azhar University,Cairo,Egypt, 3Faculty of Medicine, Al-Quds University,Jerusalem,Palestinian, State of, 4Cairo university Faculty of medicine,Cairo,Egypt, 5Faculty of Medicine, Fayoum University, Egypt.,Fayoum,Egypt, 6Faculty of Medicine Al-Azhar University,Damietta,Egypt, 7Faculty of medicine, Ain Shams university,Cairo,Egypt

To determine the efficacy of implantable Collamer lens (ICL) implantation after corneal collagen cross-linking (CXL) in keratoconus.

Department of Ophthalmology, Faculty of medicine, Al-Azhar university.

We searched PubMed, Cochrane CENTRAL, SCOPUS, Web of Science, and Google Scholar from inception until February 2023. We included the relevant studies that assessed ICL implantation post-corneal collagen cross-linking in patients with keratoconus. The efficacy endpoints were corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA), sphere, cylinder, spherical equivalent, and keratometry.

Seven observational studies were eligible for this systematic review and meta-analysis. ICL implantation showed an improvement in UVDA 6 months postoperative, with a mean change of -1.27 (95% CI [-1.63 to -0.9]. However, there was non-significant improvement in CDVA with a mean change of -0.04 Log Mar (95% CI [-0.11 to 0.02]. A trend toward the improved sphere and spherical equivalent was observed for all eyes after the ICL implantation approach: mean change of 6.82 diopters (95% CI 3.24 to 10.4) for the sphere and 7.30 diopters (95% CI [4.18 to 10.43]) for the spherical equivalent. The cylinder was not improved after ICL implantation with a mean change of 0.62 diopters (95% CI [-0.53 to 1.77].  

The ICL implantation approach appears is effective and safe for both corneal stabilization and visual acuity improvement in patients with keratoconus