Initial Experience With A Single-Piece Non-Diffractive Wavefront Modifying Extended Depth Of Focus Intraocular Lens

To evaluate the visual and refractive outcomes of a single-piece acrylic non-diffractive wavefront modifying extended depth of focus (EDOF) intraocular lens

Multidisciplinary private hospital

Prospective consecutive case series study. Inclusion criteria were eyes with visually significant cataracts and no pre-existing comorbidities. 20 patients with bilateral implantations were evaluated with all operations performed by a single surgeon in a standard manner. The dominant eye was targeted for emmetropia. Non-dominant eyes were targeted to be -0.50D post-operatively. Outcome measures at one month post-op were binocular visual acuities for distance, intermediate (66cm) and near (at 40cm), refractive predictability, and reported dysphotopsia

All 20 patients achieved 20/25 (LogMar 0.1) or better for distance unaided, 14 patients (70%) managed 20/20. For intermediate vision at 66cm, all patients could manage 20/32 (LogMar 0.2) or better, 18 patients (90%) could see 20/25 or better, and 9 patients (45%) 20/20. For near (40cm), all patients could see 20/40 (LogMar 0.3) or better, 14 patients (70%) 20/32 or better, and 7 patients (35%) managed 20/25 or better. Using the Barrett Universal II IOL formula with the manufacturer’s recommended IOL constant, 95% of eyes were within 0.75D of predicted post-op refraction, 82.5% within 0.50D and 45% within 0.25D. 80% were spectacle independent. No haloes or glare symptoms were reported by any patient.

This new non-diffractive EDOF IOL was found to provide good visual and relatively predictable refractive outcomes at one month post-op. Good binocular functional near vision was achieved by off-setting post-op refraction by up to -0.50D in the non-dominant eye. A high level of spectacle independence was observed. The IOL was well-tolerated by patients, with minimal dysphotopsia reported.