Visual Function Following The Implantation Of Diffractive Extended Depth-Of-Focus Intraocular Lenses In Eyes With Primary Open Angle Glaucoma: Comparison With Monofocal Intraocular Lenses

 While the implantation of extended depth-of-focus intraocular lenses (EDOF IOLs) in glaucomatous eyes has been discussed, there are no investigations comparing with the implantation of monofocal (mono) IOLs. This prospective study aimed to compare the visual function of EDOF and mono IOLs in eyes diagnosed primary open-angle glaucoma (POAG).

Tokyo Dental College Suidobashi Hospital and Ryuundo eye clinic

Cataract patients with POAG controlled with medical treatments and no loss in the central  visual field were included. Twenty-two eyes received EDOF IOLs (ZXR00V and ZXV150-375: J&J) and 24 eyes received mono IOLs (ZCB00V and ZCV150-375: J&J). The mean age was 67.1±9.6 and 71.0±6.4 years, respectively. At 3 months postoperatively, corrected distance visual acuity (CDVA), photopic contrast sensitivity (CSV-1000), and automated perimetry using SITA 30-2 program were evaluated. Noninferiority of CDVA and contrast sensitivity in eyes with EDOF IOLs were examined.

CDVAs of EDOF / mono IOLs were -0.17±0.10 / -0.08±0.07 logMAR. Logarithm contrast sensitivities of EDOF / mono IOLs were 1.64±0.17 / 1.66±0.21 at 3cpd, 1.75±0.19 / 1.85±0.25 at 6cpd, 1.25±0.24 / 1.41±0.24 at 12cpd, and 0.83±0.30 / 0.91±0.25 at 18cpd. MD of SITA 30-2 program of EDOF / mono IOLs were -2.76±2.30 / -4.21±3.29 dB and no statistical differences were found. CDVA  and contrast sensitivities at all spatial frequencies in eyes with EDOF IOL showed no inferiority at the margins of 0.15 and 0.20, respectively.

 Visual function such as CDVA and contrast sensitivity of EDOF IOL in cases with mild POAG was not inferior to that of mono IOL.