25-G Vitrectomy Combined With Transscleral Intraocular Lens (Iol) Implantation

To measure the clinical efficacy and safety of 25-G vitrectomy combined with transscleral intraocular lens (IOL) implantation. 

We began performing 25-gauge (25G) vitrectomy combined with intrascleral IOL implantation for the treatment of no orinsufficient capsular support since 2014. In this study, we observed and analyzed the changes in efficacy indicators before and after surgery to evaluate the clinical efficacy and safety of the surgical Procedure.

In this prospective study, patients (n=39, 39 eyes) without capsule support and experiencing lens dislocation, IOL dislocation, and aphakia were enrolled and treated with 25-G vitrectomy combined with transscleral IOL implantation. Differences in visual acuity, intraocular pressure (IOP), number of corneal endothelial cells, location of IOL, postoperative anatomic success, and the recurrence rate of IOL dislocation and complications were recorded. Data paired t-tests and repeated measured ANOVA

The average visual acuity (LogMARs) at 1 week, 1 month, 3 months, and 6 months after surgery were significantly differences improved compared with the pre-surgical values (P<0.05). The average IOPs at 1 week, 1 month, 3 months, and 6 months after operation were significantly differences lower compared with the pre-surgical values (P<0.05). One week after surgery, all of the implanted IOLs were in the correct position. One month after surgery, the IOLs in 36 eyes (92%) were in the correct position. The haptics of one IOL (3%) were exposed to the conjunctiva. Dislocation of two IOLs (5%) required alignment surgery at 3 and 6 months after insertion, positions of 36 IOLs were stable.

The 25-G vitrectomy combined with transscleral IOL implantation in the treatment of eyes without capsule support was effective and safe.