ESCRS - PO0402 - Stargus: Comparative Study Of The Argos Biometer Compared To Ultrasound Biometer In B-Mode In Case Of Measure Failure With The Conventional Biometer. Interim Analysis

Stargus: Comparative Study Of The Argos Biometer Compared To Ultrasound Biometer In B-Mode In Case Of Measure Failure With The Conventional Biometer. Interim Analysis

Published 2023 - 41st Congress of the ESCRS

Reference: PO0402 | Type: Free paper | DOI: 10.82333/xpxk-q618

Authors: Héloïse Torres-Villaros* 1 , Didier Hoa 2 , Maté Streho 3 , Audrey Giocanti-Aurégan 1

1Hôpital Avicenne, APHP, Université Sorbonne Paris Nord,Bobigny,France, 2Montpellier Centre Ophtalmologie,Montpellier,France, 3Centre Explore Vision,Paris,France

Purpose

Non-contact optical biometry has become the gold-standard because of its ease of use, accuracy, and reproducibility. However, the main disadvantage of the optical methods is their inability to obtain axial length measurements in approximately 10% of eyes, typically those with dense posterior subcapsular cataracts.  

Therefore, B-mode ultrasound measurement is necessary to allow Axial Length (AL) measurements. Alcon has integrated the ARGOS® biometer’s diagnostic testing, based on swept-source optical coherence tomography (SS-OCT) which allows AL calculation even in dense cataracts. Our study aimed to compare the AL obtained on ARGOS® with the B-mode ultrasound, in the event of failure with the conventional optical biometer.

Setting

Retrospective, cross-sectional paired study on 110 eyes between August 2021 and January 2022 in 3 centers: 1 teaching hospital, 1 biometry reference center and 1 private clinic. 

Methods

The main objective was to study the concordance between the Argos biometer and B-mode ultrasound in the measurement of AL in case of dense cataract and failure of the AL measurement with conventional optical biometer. B-mode ultrasound is the reference method in such cases. Study supported by an investigator-initiated study grant from Alcon (IIT #69445453).
The primary endpoint was the measurement of AL in mm by the Argos biometer and the comparison with the AL measured by ultrasound echograph in mode B in case of failure of the measurement of AL with the conventional optical biometer.

Results

Intermediate results from 41 AL measurements were collected. Of the 41 measurements performed with Argos, it was possible to collect AL data in 92.7% of cases (38 eyes out of 41). The average AL measured with Argos was 24.63 ±3.36 mm. On this same population, the average obtained with B-mode ultrasound was 24.53 ±3.32 mm. The comparison between these measurements showed an average non-significant difference of -0.0033 ±0.12 mm, p=0.87. Results with the entire population will be further presented.

Conclusions

The first results of our study showed that the acquisition rate of the Argos biometer was 92.7% on dense cataracts where AL could not be measured by our conventional biometers. The concordance rate with mode B ultrasound was satisfactory with a non-significant difference in measurements. The results for the entire study population will be presented in September 2023.